MMSL, 2020 (vol. 89), issue 4

EFFECTS OF FLUOROQUINOLONE RESTRICTION IN THE HOSPITAL ON THE DEVELOPMENT OF SENSITIVITY OF SELECTED BACTERIAL PATHOGENSOriginal article

Pavla Paterova, Lenka Ryskova, Miroslav Fajfr, Katerina Kuncova, Katerina Neradova, Kristyna Vaverkova, Lenka Hobzova, Petr Prasil, Stanislav Plisek, Jakub Radocha, Pavel Bostik, Helena Zemlickova

MMSL 2020, 89(4):178-189 | DOI: 10.31482/mmsl.2020.014  

Introduction: Fluoroquinolones are a frequently prescribed class of antibiotics, which has been blacklisted in recent years because of a growing evidence of the connection with serious undesirable effects, infections Clostridioides difficile, and a connection with the occurrence of multiresistant strains.Methods: In the University Hospital Hradec Kralove in the course of the years 2009-2019, several antibiotic stewardship restrictive and educational interventions were performed by the Antibiotic Centre aiming to decrease quinolone antibiotics administration. The data of the consumption of quinolone antibiotics were retrospectively evaluated...

STUDY OF THE LATENT PHASE OF RADIATION-INDUCED LUNG INJURYOriginal article

Anna Lierová, Marcela Jeličová, Jaroslav Pejchal, Zuzana Šinkorová

MMSL 2020, 89(4):190-199 | DOI: 10.31482/mmsl.2020.015  

Early changes after radiation exposure may serve as predictors as well as targets for alleviation of radiation-induced injury in the lung. The aim of our study was to examine alterations on the cell and tissue levels in the lung and blood changes of immunological and cytokines profiles induced by ionizing radiation (IR) during the first month after irradiation in the mice experimental model. Female C57BL/6 mice were total body irradiated (TBI) by 8 Gy. Lung tissue samples and blood and were collected 4, 8 and 24 h, 7, 21 and 30 d after TBI. We measured absolute cell counts, cell populations and cytokines profile in the blood and evaluated histopathological...

ACUTE KIDNEY INJURY: SIMULATED DOSING ERROR IDENTIFICATION BY PHARMACY STUDENTSOriginal article

Elham Alshammari

MMSL 2020, 89(4):200-206 | DOI: 10.31482/mmsl.2020.018  

Pharmacists are responsible for dispensing drugs and protecting the patient by making sure that they use drugs appropriately. They play an important role not only in the overall cost implications of healthcare but also in the concerns about patient safety when using medication. The scope of this paper was to evaluate the practice of navigation of medical resources among pharmacy students through a simulated event of acute kidney injury using a prospective research methodology. A sample of 65 students was used, among which 2 failed to identify the error in dosing (3.1%) while 56 (86.2%) responded with the presence of error in renal dosing and recommended...

MEDICAL AND DENTAL STUDENTS' KNOWLEDGE AND PERCEPTIONS ABOUT ANTIMICROBIAL STEWARDSHIP: A CALL FOR EDUCATIONAL ENHANCEMENTOriginal article

Nada Alsaleh, Abeer Alsmari, Fadiyah Alanazi, Abdulmohsen Alsaleh, Rahaf Alsmari, Nasser Al-Swedan

MMSL 2020, 89(4):207-214 | DOI: 10.31482/mmsl.2020.019  

Purpose: To explore the knowledge of antibiotics use and resistance among medical and dental students.Methods: A 26-item online questionnaire on antimicrobial prescribing was distributed to Medical and Dental students at eight universities from the period of July to August 2020.Results: Five hundred three students completed the questionnaire; The mean age was 22.15 ± 1.99 and 66.4% were female students. The majority (91.5%) of the students were from governmental universities and (73.4%) were from medical colleges. It was found that 87% of students were not familiar with and unaware of the term antimicrobial stewardship. Overall knowledge about...

TERRORIST ATTACKS BY LONELY WOLFS AND ITS PREVENTIONReview article

Miroslav Pohanka, Jan Břeň

MMSL 2020, 89(4):215-220 | DOI: 10.31482/mmsl.2020.017  

The issue of lone wolfs or a lone-actor terrorists become a serious and actual security problem that does not have an easy solution. The non-organized attackers are able to target any site at any time and they can become indoctrinated by internet and a contact with a terrorist group is not a condition of their activity. Currently, all countries over the world has to prepare for an eventuality of an attack. Some regions are hardly burdened by the attackers and preparation of countermeasures is a crucial task for law enforcement units. This review paper summarizes basic knowledge in the field of lone wolfs regarding to psychological and social aspects,...

WHOLE HEALTH FOR LIFE – A PROJECT AIMED AT REDESIGNING HEALTH CARE FOR AMERICAN VETERANSReview article

Ales Kubat

MMSL 2020, 89(4):221-228 | DOI: 10.31482/mmsl.2020.009  

The Veterans Health Administration provides health care for 9 million American armed forces veterans every year. The system is currently undergoing transformation to personalized, proactive and patient-driven health care. One part of this transformation is called Whole Health for Life and is discussed in this article in greater detail with an emphasis on holistic approach and using some complementary and alternative methods, such as for example yoga. It could be inspiring for health care about both the veterans and patients with chronic health conditions in the Czech Republic.