MMSL, 2024 (vol. 93), issue 4

STUDY OF THE LEVEL OF KNOWLEDGE OF PRIMARY SCHOOL STUDENTS IN THE FIELD OF PUBLIC PROTECTION IN EMERGENCIESOriginal article

Miroslav Kopecký, Iveta Hudzietzová, Hana Střítecká

MMSL 2024, 93(4):313-322 | DOI: 10.31482/mmsl.2023.036  

Introduction: Sufficient continuous preparation is needed to ensure that citizens are able to respond adequately in the event of emergencies. This preparation is a continuous process of education in the Czech Republic that is part of primary school educational programmes.Objective: To determine the knowledge of 6th and 9th grade primary school students in the field of protection of people in emergencies.Methodology: A questionnaire survey was conducted among a group of 1,943 respondents at 19 primary schools in the Olomouc and Moravian-Silesian regions in 2018 to 2019.Results: The results showed that students in 6th,...

A SYSTEM FOR WIRELESS MEASUREMENT OF HUMAN BIOMECHANICSOriginal article

Pavel Holeka, Filip Studnička, Jan Štěpán, Jan Matyska, Jan Šlégr, Šárka Odložilová, Ján Zajak, Jiří Páral

MMSL 2024, 93(4):323-334 | DOI: 10.31482/mmsl.2023.038  

Background: Femoroacetabular impingement syndrome (FAI) is a complex, often post-traumatically developing impairment of the hip joint. It is characterized by ambiguous symptomatology, which makes early diagnosis difficult. Aim: The study was conducted to evaluate the applicability of a triaxial gyroscopic sensor in routine practice as an additional indication criterion for operative versus conservative treatment procedures. Methods: Ninety-two patients were included in the experimental retrospective study and 62 completed the examination. All patients signed informed consent. A gyroscopic sensor was placed on the right side of the pelvis above the...

A CLINICAL STUDY OF LIPOCALIN 2 AND ITS RELATION WITH OXIDATIVE AND ANTIOXIDATIVE FACTORS IN ARTHRITISOriginal article

Safa Rabea Saadon, Thikra Ali Allwsh

MMSL 2024, 93(4):335-341 | DOI: 10.31482/mmsl.2023.040  

Background: Lipocalin-2 (LCN2) is a protein that has been associated with skeletal muscle regeneration, but details regarding its role in Arthritis remain unclear. The aim of the current study was to investigate LCN2 levels of Arthritis patients and its relationship with oxidative and antioxidative factors.Methods: The study includes (125) blood samples of persons aged 20–65 years were divided into a control group (apparently healthy) consisting of 55 samples [31female, 24 males] and a Patient group consisting of 70 samples [37female, 33 males] who were attending the bone diseases consultation unit at the Ibn Sina Teaching Hospital in Mosul,...

THE SIGNIFICANCE OF SERUM MIDKINE IN THE DIAGNOSIS AND PROGNOSIS OF INVASIVE DUCTAL CARCINOMA OF THE BREASTOriginal article

Noor Al-Huda J. Muhammad, Haider A. Jabbar, Nahidh R. Kazem

MMSL 2024, 93(4):342-354 | DOI: 10.31482/mmsl.2023.043  

Background and Objectives: Initial diagnosis of brest cancer (BC) is important for fate and prognosis of the diseases profile, we sought to identify the correlation between Midkine (MK) as a new biomarker with cancer antigen (CA)15-3, liver function test, renal function test, blood cells parameters in individuals with invasive ductal carcinoma.Methods: The serum MK and CA15-3  of all subjects were measured by the ELISA technique, Liver enzymes were measured by colourimetric methods and neutrophils, and lymphocytes were measured by an Electrical Impedance Cell Counting method (automated machine).Results: The results of the correlation among serum MK...

OLEUROPEIN AND HYDROXYTYROSOL AS ANTIDIABETICS: A REVIEW ON EXTRACTION METHOD, EFFECTIVENESS AND TOXICITY EFFECTReview article

Nurhidayati Harun, I Ketut Adnyana, Sophi Damayanti, Neng Fisheri Kurniati

MMSL 2024, 93(4):355-363 | DOI: 10.31482/mmsl.2023.037  

Introduction: Olive (Olea uropeae) is a traditional plant containing oleuropein and hydroxytyrosol, which are useful and used empirically for treating diabetes mellitus.Objective: To review the potential of oleuropein and hydroxytyrosol as an evidence base for diabetes potential treatment and safety.Methods: This chapter summarizes several studies available on Pubmed and Google Scholar regarding the characteristic method and extraction method as well as the effectiveness and toxicity of oleuropein and hydroxytyrosol in vitro and in vivo.Result: Oleuropein and hydroxytyrosol are effective antihyperglycemics for treating T2D. They can reduce body weight,...

JUVENIL, A NATURAL IMMUNE BOOSTER AFFECTING BIOLOGICAL RESPONSES THROUGH MODULATION OF GUT MICROBIOTA COMPOSITIONReview article

Vanda Bostik, Klára Kubelková, Aleš Macela

MMSL 2024, 93(4):364-376 | DOI: 10.31482/mmsl.2023.039  

Juvenil, a nontoxic extract of bovine blood, is registered as a dietary supplement having no side effects. It contains a broad spectrum of free amino acids, as well as small proteins and oligopeptides (molecular weights up to 10 kDa), various nucleotides, and small amounts of phospholipids. The complex of these exclusively natural components has been shown to support physiological responses of supplemented organisms.Juvenil has been studied for several decades using a wide range of both experimental and clinical studies. Analyses have shown that it acts directly neither on individual functional systems of the body nor on individual metabolic processes....

THE DIABETIC-ANEMIA NEXUS: IMPLICATIONS FOR CLINICAL PRACTICEReview article

Ghada M. Ahmed, Mohammed N. Abed, Fawaz A. Alassaf

MMSL 2024, 93(4):377-387 | DOI: 10.31482/mmsl.2023.042  

Objectives: Due to a variety of factors, individuals with diabetes are more likely to develop anemia. Chronic kidney disease, a frequent consequence of diabetes, is one of the key contributing factors. Diabetic neuropathy is another reason that can result in gastrointestinal bleeding and iron malabsorption. Healthcare providers must be aware of the connection between diabetes and anemia in order to closely monitor and treat both disorders and lessen their detrimental effects on general health and quality of life. This review sought to explore the underlying factors that lead to anemia in diabetic individuals, as well as the most prevalent kinds of...