VZL 2001, 70(1):39-42
POSSIBILITIES OF PROTEIN EXPRESSION MEASUREMENT IN IMMUNOHISTOCHEMICAL APOPTOSIS DETECTION IN THE IRRADIATED LUNG TISSUE EXAMPLE
- Michal Králik1, Jan Österreicher1, Leoš Navrátil2, Jiří Knížek1, Jiřina Vávrová1, Jiří Škopek2, Aleě Macela
ORCID...1 - 1 Department of Radiobiology and Immunology, Purkyně Military Medical Academy, Hradec Králové
- 2 Group of the Clinical Radiobiology, the 1st Medical Faculty of Charles University, Prague
This study observes the development of apoptotic changes in type II pneumocytes in a time interval of 1, 2, 3, 4, 5, 8 and 12 weeks after local irradiation of the lungs with 15 Gy. We also measured the number of neutrophils in the lung tissue. Elevation of the apoptotic cells was observed 2 weeks and 4 weeks after irradiation. An increase in neutrophil infiltration was observedfrom 5 weeks after irradiation.
Keywords: Radiobiology; Apoptosis; Immunohistochemistry; Detection
Published: February 1, 2001 Show citation
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Králik, M., Österreicher, J., Navrátil, L., Knížek, J., Vávrová, J., Škopek, J., & Macela, A. (2001). POSSIBILITIES OF PROTEIN EXPRESSION MEASUREMENT IN IMMUNOHISTOCHEMICAL APOPTOSIS DETECTION IN THE IRRADIATED LUNG TISSUE EXAMPLE. Vojenské Zdravotnické Listy, 70(1), 39-42
