MMSL, 2023 (vol. 92), issue 3

EVALUATION OF THE EFFECTS OF N-ACETYLCYSTEINE ON SERUM GLUCOSE, LIPID PROFILE, AND BODY WEIGHT IN RATS WITH FRUCTOSE-INDUCED METABOLIC SYNDROMEOriginal article

Auss Z. Yahya, Ghada A. Taqa, Muhammad A. Alkataan

MMSL 2023, 92(3):194-207 | DOI: 10.31482/mmsl.2022.039  

Background: Overconsumption of fructose may cause metabolic syndrome (MetS). MetS pathogenesis is caused by oxidative stress, cellular malfunction, and systemic inflammation caused by hereditary and environmental factors. N-acetylcysteine (NAC) has become associated with the phrase "antioxidant." Most researchers use and test NAC with the goal of preventing or reducing oxidative stress.Aim: To determine the positive effects of NAC on blood glucose, lipid profile, and body weight in fructose-induced metabolic syndrome in albino rats.Materials and Methods: Forty male albino rats, 10-12 weeks old, were haphazardly divided into five groups of identical...

EVALUATION OF ALFAXALONE'S ANTI-INFLAMMATORY AND ANTINOCICEPTIVE EFFECTS IN BROILER CHICKSOriginal article

Amjed Najem Alatroshi, Ahmed Salah Naser

MMSL 2023, 92(3):208-216 | DOI: 10.31482/mmsl.2022.042  

Background: Progesterone is the source of the steroid general anesthetic Alfaxalone, which became commercially available in the 1970s when combined  with alfadolone, another steroid anesthetic.Objective: the goal of the present  research was to discover and assess the sub-anesthetic effects of Alfaxalone: the antinociceptive and anti-inflammatory properties in broiler chicks. Methods: One hundred and three Ross broiler chicks (80-100 g, 7-8 days old) were used. The electric stimulation test, hot water test (HWT), and formalin test were performed on broiler chicks to assess the antinociceptive and anti-inflammatory properties of Alfaxalone. The up-and-down...

MOTHERS’ KNOWLEDGE AND PRACTICE REGARDING HEALTHY NUTRITION AMONG BLIND CHILDREN IN MOSUL CITYOriginal article

Ali A. Shareef, Marab YA. Al-Fathy, Sakeena AJ. Al-Tameemi, Montha H. Ismaeel

MMSL 2023, 92(3):217-225 | DOI: 10.31482/mmsl.2022.041  

Background: Nutrition an integral part of child growth and development.Aim: Comparison regarding mothers' knowledge and practice between blind and non-blind child.Patients and Methods: A case control study design of 120 mothers (40 mother of blind child and 80 mother of non-blind child). It was adopted in UmAl-Rbean Development Foundation for Blind and purblind during.Results: revealed that 108 (90%) agree that with food we can control most of our disease. Diet-disease relationship reported by mothers were obesity 92 (77%) and hypertension 66 (55%) with P-value 0.017. Mothers' knowledge regarded true fact (playing sport and eat and drink, and do not...

A PROMISING ROLE OF CINNAMON TOWARDS RHEUMATOID ARTHRITISReview article

Ammar A.Y. Almulathanon, Zena Sideek Tawffiq

MMSL 2023, 92(3):226-234 | DOI: 10.31482/mmsl.2022.043  

Rheumatoid arthritis (RA) is a chronic disorder manifested by joint damage due to inflammation and autoimmunity which in turn has significant impacts on a patient's lifestyle. During disease, inflammation occurs due to activation of different immune cells, including macrophages and lymphocytes. Currently, the mainstay of treatment for RA is drug therapy. However, drug options are limited due to their negative effects and the possibility of reducing therapeutic benefits over time. Therefore, an effective and tolerable alternative therapy is needed. Several natural products have been found to have anti-inflammatory and anti-oxidant effects by affecting...

ON THE INVOLVEMENT OF CBRN AND MEDICAL SPECIALISTS IN THE EXPLOITATION OF FACILITIES SUSPECTED FOR THE PRESENCE OF BIOLOGICAL MATERIALOriginal article

Radim Zahradníček, Tomáš Rozsypal, Hynek Schvach

MMSL 2023, 92(3):235-246 | DOI: 10.31482/mmsl.2022.045  

The existence of chemical, biological, radiological, and nuclear (CBRN) weapons poses a significant problem in terms of possible proliferation of technologies and materials, despite international agreements and regulations. The role of military forces in operations can be to support counter-proliferation initiatives to prevent their acquisition, deployment, or employment. The article analyzes the current situation in the field of site exploitation under CBRN environments, with a specific focus on biological threats. It describes a current state and a research question, which is addressed on the basis of scenario analysis methodology. The result is...

THE PROTECTIVE EFFECT OF BETA CAROTENE AGAINST AMIKACIN INDUCED NEPHROTOXICITYOriginal article

Muthanna T. Khalaf, Zeina A. Althanoon

MMSL 2023, 92(3):247-258 | DOI: 10.31482/mmsl.2022.037  

Background: The rapid loss of kidney function is known as nephrotoxicity. The harmful effects of medications may cause this. Amikacin-related nephrotoxicity is an excellent illustration of such a case. Amikacin is a synthetic aminoglycoside that works against the majority of gram-negative bacteria and, in some circumstances, can be harmful to the kidneys. One of the many methods used to prevent or decrease this toxicity is the use of antioxidant substances with amikacin. Beta carotene is an antioxidant carotenoid pigment.The aim of the current study: is to illustrate the ameliorative effect of beta carotene against the nephrotoxicity caused by amikacin...

IMPACT OF SCREEN EXPOSURE ON LANGUAGE DEVELOPMENT AMONG TODDLERS AND PRESCHOOLERS IN NINEVEH PROVINCEOriginal article

Zainab Waleed Aziz, Elham K. Aljammas, Luma I.K. Al-Allaf

MMSL 2023, 92(3):259-271 | DOI: 10.31482/mmsl.2022.048  

Background: There is a marked use of technology by children in our societies, particularly during the last 2decades, which may be associated with limitation of their milestones developments including speech.Objectives: To determine the association between screen exposure and speech development delay among toddlers and preschoolers, to clarify the correlation linking the visioning of the screen and the input - data – of the child and his(her) mother, and to identify the impact of screen withdrawal on the possible enhancement of speech.Material and Methods: This descriptive cross-sectional study enrolled children (n=237) who had a history of delay...

PEROXIREDOXIN 3 WITH TOXIC METALS IN MISSED ABORTION PATIENTSOriginal article

Israʼa H. AL-Hamdani, Luay A. Al-Helaly

MMSL 2023, 92(3):272-279 | DOI: 10.31482/mmsl.2022.050  

The most vital factors that hostile health human are toxic heavy metals (THMs). Heavy metals are harmful environmental contaminants that can decrease the likelihood of a healthy pregnancy and afterwards impede a healthy birth. Both paternal and maternal toxic metal exposure could influence pregnancy, So the rates of pregnancy failure are constantly rising. The current study's goal is to explore the effect of Pеrоxirеdоxin 3 antioxidant, as well as some toxic metals (TMs) such as arsenic, cadmium and mercury in missed abortion patients and compared with healthy pregnant and non˗pregnant women without a history of abortion...

ASSESSMENT OF OXIDATIVE STRESS AND ANTIOXIDANT STATUS IN TYPE 1 DIABETES MELLITUSOriginal article

Fatimah Haitham Fathi, Jehan A. Mohammad, Ammar A.Y. Almulathanon

MMSL 2023, 92(3):280-286 | DOI: 10.31482/mmsl.2023.015  

Increased oxidative stress appears to be a risk factor for insulin resistance, dyslipidemia, β-cell dysfunction, impaired glucose tolerance, and, eventually, diabetes mellitus. The majority of research shows that oxidative stress plays a role in the etiology of diabetes through changes in enzymatic systems, lipid peroxidation, decreased levels of vitamin C, and reduced glutathione metabolism. Objectives: the study was conducted to evaluate biomarkers of oxidative stress such as serum malondialdehyde (MDA), myeloperoxidase (MPO), catalase (CAT), vitamins (C, E), nitric oxide (NO), reduced glutathione (GSH) levels and a lipid profile in newly diagnosed...

14th HOST-PATHOGEN INTERACTION FORUM 2022: A MULTIDISCIPLINARY VISION ON THE HOST-PATHOGEN MUTUAL INTERACTIONLetter to the editor

Klára Kubelková

MMSL 2023, 92(3):287-288  

The 14th Host-Pathogen Interaction Forum was held in Kutná Hora, Czech Republic, between November 7 - 10, 2022. The Forum was traditionally organized by the Faculty of Military Health Sciences, Hradec Králové, Czech Republic, in collaboration with the Czech Immunological Society in Prague, Czech Republic.