MMSL, 2017 (vol. 86), issue 3

ÚSPĚŠNÁ CESTA STŘEDOŠKOLSKOU ODBORNOU ČINNOSTÍ (SOČ)Letter to the editor

Adam Anthony Needle, Vendula Hepnarová

MMSL 2017, 86(3):94-95  

ANALYSIS OF NERVE AGENTS THROUGH A MODIFIED METHOD OF CHOLINESTERASE ASSESSMENT USING ARTIFICIAL NEURONAL NETWORKSOriginal article

Monika Hoskovcová, Pavel Dubina, Emil Halámek, Zbyněk Kobliha

MMSL 2017, 86(3):96-103 | DOI: 10.31482/mmsl.2017.017  

A simple colorimetric biosensor, which uses the modified Ellman's reaction, enables selective analysis of nerve agents based on a different ability of bispyridinium oximes to reactivate enzyme-inhibitor complexes in the phase before dealkylation. The analysis was made based on spectral data of reflectance of the surface of a cotton cloth reaction zone of biosensor with immobilized and stabilized enzyme after inhibition and subsequent reactivation. The evaluation of measured data was made based on a method of artificial neuronal networks. The individual inhibitors from the groups of three nerve agents were identified: sarin, soman, tabun, cyclosarin,...

ZAJÍMAVOSTI ZE SVĚTA ARBOVIROVÝCH NÁKAZReview article

Vanda Boštíková, Nora Boštíková, Pavel Boštík

MMSL 2017, 86(3):104-113 | DOI: 10.31482/mmsl.2017.018  

CHEMOTERAPEUTIKUM DAPSON - ZÁKLADNÍ CHARAKTERISTIKA A ZAJÍMAVÉ VÝSLEDKY KLINICKÝCH STUDIÍReview article

Miloslav Salavec, Vanda Boštíková, Nora Boštíková, Pavel Boštík

MMSL 2017, 86(3):114-121 | DOI: 10.31482/mmsl.2017.019  

PHARMACOLOGICALLY AND TOXICOLOGICALLY RELEVANT COMPONENTS OF Amanita muscariaReview article

Jiří Patočka, Barbora Kocandrlová

MMSL 2017, 86(3):122-134 | DOI: 10.31482/mmsl.2017.020  

Amanita muscaria, the red fly agaric, is the most famous of all Amanita. The initial history of this fascinating mushroom dates back to at least the 13th century. The use of mushrooms began in antiquity and is associated with mysticism. The collection and consumption of mushrooms and other plants containing psychoactive substances is now very popular, especially among young people who are experimenting with drugs. Ibotenic acid and muscimol are the main active ingredients of this mushroom, but other substances are likely to be involved in the psychotropic effects. A. muscaria also contains some other non-psychotropic substances...

GIANT HOGWEED AND PHOTODERMATITISReview article

Jiří Patočka, Klára Cupalová

MMSL 2017, 86(3):135-138 | DOI: 10.31482/mmsl.2017.021  

Giant hogweed (Heracleum mantegazzianum) is a member of the parsley or carrot family (Apiaceae). As its name indicates it is characterized by its size and may grow up to 4 meters in height. Giant hogweed is native to the Caucasus mountains and southwestern Asia and has been introduced to Europe, the United Kingdom, Canada and the United States as a garden curiosity. Because of its tenacious and invasive nature it soon becomes a pest within the ornamental garden and readily escapes. It has naturalized in many of the places where it was first introduced. All parts of the plant are poisonous and giant hogweed is toxic to livestock and humans....

DVOUDENNÍ KONGRES NA POČEST DLOHOLETÉ PŘEDSEDKYNĚ SEKCE CHIRURGICKÝCH OBORŮ, PANÍ EVY KVASNICOVÉAnnouncement

Iva Otradovcová, Lucie Kubátová

MMSL 2017, 86(3):139  

17th INTERNATIONAL NUTRITION & DIAGNOSTICS CONFERENCE INDC 2017Announcement

Iveta Plecháčová

MMSL 2017, 86(3):140  

Following the success of the previous International Nutrition & Diagnostics Conference we are delighted to invite you to the next year's event on 9 - 12 October 2017 in Prague, Czech Republic.INDC 2017 will once again bring together medical doctors, analytical chemists, biochemists, chemists, and those in the clinical diagnosis seeking research breakthroughs, new technologies and new approaches in the field of nutrition, food diseases, food components and health trends.Nutrition, food science and diagnostics have improved their importance in today's human's life style. Food diseases, nutritional disorders, and malnutrition habits are becoming major...