MMSL, 2020 (vol. 89), issue 3
GUT MICROBIOTA ALTERATIONS BY NUTRITIONAL SUPPLEMENT IMUREGENOriginal article
Klara Kubelkova, Ivan Rychlik, Magdalena Crhanova, Daniela Karasova, Dasa Slizova, Jitka Zakova, Lenka Luksikova, Ales Macela
MMSL 2020, 89(3):114-125 | DOI: 10.31482/mmsl.2020.008 
The gut microbiota is one of the modulators influencing its host’s development, metabolism, as well as immunological, psychological, and cognitive abilities. The gut microbiota consortium influences enteroendocrine regulation, neurohormonal regulation, as well as natural immune regulation. Disruptions occurring in life can lead to dysbiosis that in turn influences the host homeostasis and/or disease. Targeted modulation of microbiota composition thus appears to be an appropriate intervention strategy in cases of certain specific health problems. Here, we demonstrate that application of the nutritional supplement Imuregen, which is a natural immune...
OPCW BIOMEDICAL PROFICIENCY TEST IN THE LABORATORY OF ANALYTICAL CHEMISTRY AT THE DEPARTMENT OF TOXICOLOGY AND MILITARY PHARMACYOriginal article
David Herman, Alžběta Dlabková, Nela Váňová, Lukáš Prchal, Marie Vajrychová, Rafael Doležal, Petr Bzonek, Daniel Jun
MMSL 2020, 89(3):126-141 | DOI: 10.31482/mmsl.2020.011
Taking into account the events of recent years, a risk of exposure to high toxic substances including chemical weapons is not negligible. Therefore the Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence introduced analytical and biological samples (plasma, urine) preparation methods for determination of biomarkers of exposure to nerve agent (sarin, cyclosarin, soman, tabun, VX and VR agent) and sulphur mustard. Evidence of chemical weapon use is based on detection of their metabolites (Alkyl methylphosphonic acids as metabolites of the organophosphorus nerve agents, thiodiglycol as a metabolite...
COVID-19 AWARENESS IN KUWAITI HOSPITALSOriginal article
Elham Alshammari, Nada Alsaleh, Ahlam Alshammari, Alaa Alsharif, Abdulmohsen Alsaleh, Meshari Alhamed, Abeer Alsmari, Anfal Alshammari
MMSL 2020, 89(3):142-150 | DOI: 10.31482/mmsl.2020.016
As of 14th July 2020, 12,964,809 confirmed cases of coronavirus (COVID-19) and 570,288 deaths had been reported globally. In Kuwait, the numbers stood at 55,508 confirmed cases and 393 deaths. The disease seems to be hitting hard on the country despite the measures that have been put in place. The current study sought to examine healthcare workers HCWs awareness and perceptions of coronavirus disease in Kuwait hospitals. A prospective study design was used to examine the development of the disease among 28 HCWs between mid-May and the start of June 2020. The primary findings were as follows; most of the study participants had attended lectures/...
TESTING OF DYNAMIC STABILITY LOWER LIMB ACCORDING TO THE Y BALANCE TEST IN PROFESSIONAL JUDOKAOriginal article
Repová K, Líška D, Kubas V
MMSL 2020, 89(3):151-159 | DOI: 10.31482/mmsl.2020.013
Introduction: Judo is one of the most common martial arts around the world. Lower limb injuries in judo are a significant issue. Optimal dynamic stability plays an important role in injury prevention. Due to the high risk of injury to the lower limbs, we decided to test the dynamic stability of professional judokas of the Military Sports Center DUKLA Banská Bystrica.Method: The Y Balance Test (YBT) is a device used as a test to measure dynamic stability and determine the potential risk of lower limb injury. When measuring the athlete's lower limbs, YBT requires maintaining balance, strength, coordination and stability on one leg while moving the other...
BEHIND THE SCENES OF HOST–MICROBE INTERACTIONSReview article
Magdaléna Prokšová, Jiří Stulík, Klára Kubelková
MMSL 2020, 89(3):160-176 | DOI: 10.31482/mmsl.2020.010
Interaction between a host cell and pathogen is a permanent event and can have either adverse outcome leading to disease or great benefit for their mutual co-existence. Understanding pathological host–pathogen interaction is a prerequisite for unveiling the strategies of pathogens virulence. A number of methods exist today for deciphering and characterizing host–pathogen interaction. To increase their sensitivity and accuracy, these methods are commonly used in combinations, such as affinity purification and liquid chromatography–mass spectrometry analysis, cross-linking together with liquid chromatography–mass spectrometry...