MMSL, 2018 (vol. 87), issue 1
ETHICAL DILEMMAS OF POSTPARTUM PATIENTS WITH A HISTORY OF DRUG USE FROM U.S.Review article
Iva Holmquist, Vanda Boštíková
MMSL 2018, 87(1):2-7 | DOI: 10.31482/mmsl.2018.001 
Pregnant or postpartum patients with history of substance use disorder who desire to breastfeed present healthcare providers with numerous issues as drug use increases risk for adverse health outcomes for both the mother and her child. Drug use in the U.S. is common. In 2013, an estimated 24.6 million Americans aged 12 or older were current illicit substance users representing 9.4 % of the population. This statistic unfortunately closely corresponds with substance use in pregnant women. Totally 9% of pregnant women used drugs during their first trimester. Substance use during pregnancy and during breastfeeding presents serious problem for the health...
MICROBIAL PROTEASES AND THEIR APPLICATIONSReview article
Tomáš Válek, Miroslav Pohanka
MMSL 2018, 87(1):8-13 | DOI: 10.31482/mmsl.2018.002
Proteases are enzymes microbial, plant or animal origin with crucial importance in the basic metabolism. It is also a suitable material for biotechnological applications in a wide range of fields of interests like food industry, cleaning agents and medicine applications. This review paper surveys basic data about proteases and provides representative examples of their application.
BOLESATINE, A TOXIC PROTEIN FROM THE MUSHROOM RUBROBOLETUS SATANASReview article
Jiří Patočka
MMSL 2018, 87(1):14-20 | DOI: 10.31482/mmsl.2018.003
Rubroboletus satanas (Lenz) Kuan Zhao & Zhu L. Yang, known as Boletus satanas (Lenz) until 2014, and commonly known as the Devil´s bolete or Satan´s bolete, is a basidiomycete mushroom of the bolete family. Grows in mixed woodlands in the southern, warmer regions of Europe and North America. Satan´s bolete generally regarded as a poisonous mushroom, with predominantly gastrointestinal symptoms of nausea and violent vomiting occurring if eaten raw or isufficiently heat-treated. The toxicity of the mushroom corresponds to a toxic protein called bolesatine. Bolesatine is a toxic glycoprotein which has been shown to inhibit protein synthesis...
ANALYSIS OF THE 3rd YEAR STUDENTS´ FIELD TRAININGReview article
Milan Růžička, Zbyněk Suchánek, Jaroslav Žďára, Petr Smola, Jan Krutiš, Matěj Fink
MMSL 2018, 87(1):21-28 | DOI: 10.31482/mmsl.2018.004
An integral part of the education and training of students of the 3rd year of the Faculty of Military Health Sciences at the University of Defense (hereinafter referred to as FMHS UD) in Hradec Králové are subjects "Preparation in the field III" and “Organization and tactics of the Medical Service”. These subjects are organized and taught by the Department of Military Healthcare Organization and Management (hereinafter referred to as K-302).Moreover, these subjects are related to the education and training of students of the 1st and the 2nd year in the subject of "Preparation in the field I and II", which is focused...
A BRIEF HISTORY OF THE ESTABLISHMENT AND ACTIVITIES OF THE CZECH SOCIETY OF MILITARY PHYSICIANS, PHARMACISTS AND VETERINARIANSReview article
Leo Klein, Josef Fusek
MMSL 2018, 87(1):29-33 | DOI: 10.31482/mmsl.2018.005
The Czech Society of Military Physicians and Pharmacists was established in 1999, within the framework of the J.E. Purkinje Czech Medical Association. This article describes the historical circumstances and conditions that enabled the foundation of this professional society. Additionally, a brief overview of the society´s development and activities, both past and present, is also provided. Since it was established, the organization hes expanded to also include military veterinarians. Today, the society enjoys a welldeserved reputation imbued with great respect and prestige and successfully represents the field of military medicine both at home and abroad.
PRO-COGNITIVE EFFECT OF BIS(7)-TACRINE AS POTENTIAL THERAPEUTIC AGENT AGAINST NEURODEGENERATIVE DISORDERSReview article
Jan Korábečný
MMSL 2018, 87(1):34-44 | DOI: 10.31482/mmsl.2018.006
The acetylcholinesterase (AChE) structure elucidation has significantly contributed to the development of both novel homo- and heterodimer molecules that are capable of simultaneous binding to both anionic sites of the enzyme. This mostly resulted into improved AChE inhibition potency concurrently affecting other pathological hallmarks of the disease. In this regard, bis(7)-tacrine can be considered as the pioneering molecule. It consists of two tacrine moieties connected via alkylene tether of seven carbon atoms. In in vitro and in vivo, bis(7)-tacrine revealed interesting multipotent profile capable to affect several enzymes and receptors...
BRIGADIER GENERAL (RET.) ASSOC. PROF. LEO KLEIN, MD, CSC., WAS AWARDED HONORARY MEMBERSHIP OF THE J. E. PURKINJE CZECH MEDICAL ASSOCIATION AND THE COMMEMORATIVE MEDAL OF THE MILITARY MEDICAL CORPSLetter to the editor
Jan M. Horáček
MMSL 2018, 87(1):45-46
On 15th November, 2017, the 17th Conference of the Society of Military Physicians, Pharmacists and Veterinarians of the J. E. Purkinje Czech Medical Association was held in Hradec Králové. With the abundant participation of more than 90 registered participants, a festive block was included in the opening ceremonial, where various awards were presented to several members of our Society. Among them, there was also a founding member of the Society and the long-time chairman of its committee, retired Brigadier General, Assoc. Prof. Leo Klein, MD, CSc., who was awarded Honorary Membership of the J. E. Purkinje Czech Medical Association...
VITATOX 2018Announcement
Lenka Šafaříková
MMSL 2018, 87(1):47
XVIII. KONFERENCE VOJENSKÉ ZDRAVOTNICKÉ SLUŽBYAnnouncement
Jaroslav Žďára
MMSL 2018, 87(1):48