MMSL 2002, 71(S1):32-35
CYTOKINE AND CHEMOKINE MRNA EXPRESSION DURING IN VITRO INFECTION OF PHAGOCYTIC CELLS — CURRENT STATE OF STUDY
- 1 Proteome Center for the Study of Intracellular Parasitism Of Bacteria, Purkyně Military Medical Academy, Hradec Králové, Czech Republic
- 2 Faculty of Medicine in Hradec Králové, Charles University, Czech Republic
The aim of this work is to analyze the expression of eukaryotic genome of the phagocytic cell after infection with microorganism, in particular after infection with Francisella tularensis. Mouse macrophage cell line J774 is used in experiments as a model of phagocytic cell. The first part of activities which should lead to reach the aim was selecting of suitable markers of the infection. The expression of these markers should be affected by the infection of phagocytes. We chose some cytokines, chemokines and also enzymes....
Keywords: phagocytic cell; Francisella tularensis
Published: December 2, 2002 Show citation