VZL 2007, 76(5):192-199

The Effect of Selected Demographic, Psychosocial and Healthy Aspects on Quality of Life of Patients with Multiple Myeloma and Acute Myeloid Leukaemia Undergoing Autologous Haematopoietic Stem Cell Transplantation: A Retrospective Analysis (Dissertation thesis)

Ladislav Slováček1,2
1 University of Defence, Faculty of Military Health Sciences, Department of Field Internal Medicine, Hradec Kralove, Czech Republic
2 University Hospital and Faculty of Medicine of Charles University in Prague, Department of Clinical Oncology and Radiotherapy, Hradec Kralove, Czech Republic

Aim: The study analyses the quality of life (QoL) in patients with multiple myeloma (MM) and acute myeloid leukaemia (AML) undergoing autologous haematopoietic stem cell transplantation (HSCT).

Patients and Methods: The total number of respondents with AML was 12 (7 male, 5 female). The total number of respondents with MM was 32 (18 male, 14 female). The average age of patients with AML was 47.5 years and average age of patients with MM was 60 years. The Czech version of an international generic European Quality of Life Questionnaire - Version EQ-5D was used. The effect of selected psychosocial, health and demographic aspects on QoL in patients was determined by means of variance analysis. The descriptive analysis was used for evaluation of QoL questionnaires.

Results: The above-mentioned aspects proved a statistically significant dependence of QoL (EQ-5D score and EQ-5D VAS) on age in both cohorts (p<0,01), religion in AML cohort (p<0,05), smoking abuse in both cohorts (p<0,01), level of education in AML cohort (p<0,05), increasing number of associated diseases in both cohorts (p<0,05) and type of disease (p<0,05).

Conclusion: The global QoL in patients with AML is at a higher level than in patients with MM treated by means of autologous PSCT.

Keywords: Quality of life; Haematopoietic stem cell transplantation; Acute myeloid leukaemia; Multiple myeloma

Received: April 4, 2007; Published: December 1, 2007  Show citation

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Slováček, L. (2007). The Effect of Selected Demographic, Psychosocial and Healthy Aspects on Quality of Life of Patients with Multiple Myeloma and Acute Myeloid Leukaemia Undergoing Autologous Haematopoietic Stem Cell Transplantation: A Retrospective Analysis (Dissertation thesis). Vojenské Zdravotnické Listy, 76(5), 192-199
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