MMSL 2017, 86(1):17-31 | DOI: 10.31482/mmsl.2017.004

BIOLOGICALLY ACTIVE COMPOUNDS OF KNOTWEED (Reynoutria spp.)Review article

Jiří Patočka ORCID...1,2*, Zdeňka Navrátilová3, Maribel Ovando4
1 Institute of Radiology, Toxicology and Civil Protection, Faculty of Health and Social Studies, University of South Bohemia České Budějovice, České Budějovice, Czech Republic
2 Biomedical Research Centre, University Hospital, Hradec Kralove, Czech Republic
3 Department of Botany, Faculty of Science, Charles University in Prague
4 Department of Scientific and Technological Research DICTUS, University of Sonora, Sonora, Mexico

Knotweeds (Reynoutria Houtt.) are plants native to the Far East. Japanese knotweed was introduced from Japan to the unsuspecting West by the horticultural activities of Philippe von Siebold via his nursery at Leiden in the 1840s. By 1854, the plant had arrived at the Royal Botanic Gardens in Edinburgh. The plants were then sold by a large number of commercial nursery gardens around the country. Further vegetative spread followed naturally along watercourses. The knotweed is currently extremely persistant invasive plant. There is also an important source of many bioactive substances which could be used in biomedicine. The article discusses biomedically relevant constituents and its pharmacological and toxicological properties.

Keywords: Knotweed; Reynoutria; Invasive plant; Bioactive compounds; Pharmacology; Toxicology

Received: November 12, 2016; Revised: February 3, 2017; Published: March 10, 2017  Show citation

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Patočka, J., Navrátilová, Z., & Ovando, M. (2017). BIOLOGICALLY ACTIVE COMPOUNDS OF KNOTWEED (Reynoutria spp.). MMSL, 86(1), 17-31. doi: 10.31482/mmsl.2017.004
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