MMSL 2017, 86(4):158-162 | DOI: 10.31482/mmsl.2017.027

VIRAL HEPATITIS E - STILL A LOT OF UNKNOWNSReview article

Hana Střítecká ORCID...1, Vanda Boštíková ORCID...2*
1 katedra vojenského vnitřního lékařství a vojenské hygieny, Fakulta vojenského zdravotnictví v Hradci Králové, Univerzita obrany v Brně, Česká republika
2 katedra epidemiologie, Fakulta vojenského zdravotnictví v Hradci Králové, Univerzita obrany v Brně, Česká republika

Virus hepatitidy E (VHE) je odpovědný jak za epidemický, tak i za endemický výskyt hepatitidy E v lidské populaci. Přenos probíhá třemi způsoby - kontaminovanou vodou, kontaminovanými potravinami nebo zoonotickou transmisí. Mnoho aspektů týkajících se patogeneze, replikace, stejně jako imunitní odpovědi napadeného organizmu vůči tomuto viru zůstává neznámých. Lze shrnout, že VHE je dosud extrémně málo studovaným, ale přitom velmi významným lidským patogenem.

Keywords: Hepatitida E; transmise; epidemie; endemický výskyt; genotypy

Hepatitis E virus is responsible for epidemics and also endemics of this kind of diseases in humans, through waterborne, foodborne and zoonotic transmissions. A lot of aspects of VHE pathogenesis, replication, and immunological responses remain unknown up to this time. The virus is an extremly understudied but on other hand important human pathogen.

Keywords: Hepatitis E; transmission; epidemics; endemics; genotypes

Received: July 22, 2017; Revised: September 13, 2017; Published: December 8, 2017  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Střítecká, H., & Boštíková, V. (2017). VIRAL HEPATITIS E - STILL A LOT OF UNKNOWNS. MMSL, 86(4), 158-162. doi: 10.31482/mmsl.2017.027
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Kasorndorkbua C, Guenette, D K, Huang F F, Thomas P J, Meng X J and Halbur P G. Routes of transmission of swine hepatitis E virus in pigs. Journal of Clinical Microbiology. 2004;42:5047-5052. Go to original source... Go to PubMed...
    2. Montagu Vaccine & Therapeutics Biotechnology, Hepatitis E (HEV). Dostupné z: http://www.mvtbio.com/index.php/hepatitis-menu/hepatitis-e
    3. Lu L, Li C, Hagedorn C H. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Reviews in Medical Virology. 2006;16:5-36. Go to original source... Go to PubMed...
    4. Státní zdravotní ústav, Virová hepatitida E v ČR Dostupné z: http://www.szu.cz/tema/prevence/virova-hepatitida-e-v-cr?highlightWords=hepatitida
    5. Vašíčková P, Psikal I, Widen F, Smítalová R, Bendová J, Pavlík I and Králík P. Detection and genetic characterisation of Hepatitis E virus in Czech pig production herds. Research of Veterinary Science. 2009;87:143-148. Go to original source... Go to PubMed...
    6. Okamoto H. Genetic variability and evolution of hepatitis E virus. Virus Research. 2007;127:216-228. Go to original source... Go to PubMed...
    7. Mushahwar I K. Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. Journal of Medical Virology. 2008;80:646-658. Go to original source... Go to PubMed...
    8. Patra S, Kumar A, Trivedi S S, Puri M and Sarin S K. Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection. Annals of Internal Medicine. 2007;147:28-33. Go to original source... Go to PubMed...
    9. Emerson S U, Nguyen H, Graff J, Stephany D A, Brockington A and Purcell RH. Invitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein. Journal of Virology. 2004;78:4838-4846. Go to original source... Go to PubMed...
    10. World Health Organization, Media centre, Hepatitis E. Dostupné z: http://www.who.int/mediacentre/factsheets/fs280/en/
    11. Zhang M, Emerson S U, Nguyen H, Engle R, Govindarajan S, Blackwelder W C, Gerin J and Purcell R H. Recombinant vaccine against hepatitis E: duration of protective immunity in rhesus macaques. Vaccine. 2002;20:3285-3291. Go to original source... Go to PubMed...
    12. Purcell R E, Emerson S U. Hepatitis E Virus. In Fields Virology, 4th ed., Philadelphia, PA, USA; 2001. p. 3051-3061.
    13. Teshale E H, Hu D J. The two faces of hepatitis E virus. Clin Infect Dis. 2010;51:328-334. Go to original source... Go to PubMed...
    14. Seminati C, Mateu E, Peralta B, se Desu N, Martin M. Distribution of hepatitis E virus infection and its prevalence in pigs on commercial farms in Spain. Vet J. 2008;175:130-132. Go to original source... Go to PubMed...
    15. Olsen B, Axelsson-Olsson D, Thelin A, Weiland O. Unexpected high prevalence of IgG antibodies to hepatitis E virus in Swedish pig farmers and controls. Scand J Infect Dis. 2006;38:55-58. Go to original source... Go to PubMed...
    16. Emerson S, Arankalle V, Purcell R. Thermal stability of hepatitis E virus. J Infect Dis. 2005;192:930-933. Go to original source... Go to PubMed...
    17. Diez-Valcarcw M, Kokkinos P, Soderberg K, Bouwknegt M, Willems K. Occurence of human enteric viruses in commercial mussels at retail level in three European countries. Food Environ Virol. 2012;4:73-80. Go to original source... Go to PubMed...
    18. Tyrrel S F, Quinton J N. Overland flow transport of pathogens from agricultural land receiving faecal waters. J Appl Microbiol. 2003;94:87S-93S. Go to original source... Go to PubMed...
    19. Pavio N, Meng X J, Renou C. Zoonotic hepatitis E: Animal reservoirs and emerging risks. Vet Res. 2010;41:46-48. Go to original source... Go to PubMed...

    Return to the content