MMSL 2018, 87(2):74-81 | DOI: 10.31482/mmsl.2018.010

DIAGNOSIS OF AUTOIMMUNE DISEASESReview article

Adam Kostelník ORCID...1,2, Miroslav Pohanka ORCID...2*
1 Katedra biologických a biochemických věd, Fakulta chemicko-technologická, Univerzita Pardubice
2 Katedra molekulární patologie a biologie, Fakulta vojenského zdravotnictví, Univerzita obrany

Jako autoimunitní označujeme ty choroby, které jsou způsobeny reakcí imunitního systému proti zdravým, tělu vlastním strukturám. Diagnostika takovýchto stavů vyžaduje souhru klinické části s částí laboratorní. Tento text se zaměřuje na diagnostiku vybraných systémových a orgánově specifických autoimunitních chorob. Neklade si ale za cíl podrobně popsat jednotlivé choroby, spíše shrnuje nejvýraznější vodítka vedoucí k jejich správné diagnóze. Rovněž nastiňuje používané laboratorní metody a shrnuje jejich výhody a nevýhody.

Keywords: Autoimunitní choroby; diagnostika; protilátky; laboratorní diagnostika; imunoanalytické metody

Autoimmune diseases are caused by reaction of immune system against own body´s healthy structures. Diagnostics of these states require collaboration between clinical and laboratory diagnostic part. This text is focusing on diagnostics selected systemic and organ specific autoimmune diseases. It does not aim for detail description of selected diseases rather summarizing the main clues leading to right diagnostics. Also suggesting laboratory methods used in diagnostics and summarizing their benefits and drawbacks.

Keywords: Autoimmune diseases, diagnostics, antibodies, laboratory diagnostics, immunoanalytical methods

Received: October 30, 2017; Revised: November 19, 2017; Prepublished online: April 16, 2018; Published: June 8, 2018  Show citation

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Kostelník, A., & Pohanka, M. (2018). DIAGNOSIS OF AUTOIMMUNE DISEASES. MMSL, 87(2), 74-81. doi: 10.31482/mmsl.2018.010
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