MMSL 2021, 90(4):158-164 | DOI: 10.31482/mmsl.2021.025

THE EFFECT OF FLAVONOIDS EXTRACTS FROM HAWTHORN (CRATAGUS OXYACANTHUS) AGAINST SOME GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA SPECIESOriginal article

Farah H. Omer, Khadeeja Y. Abid, Manal F. Mohammed
College of Pharmacy, University of Mosul, Mosul, Iraq

The present study has shown the screening test of Hawthorn fruits (Crataegus spp.) using crude hydro-alcoholic extract and in vitro antimicrobial activity of extracted flavonoid which has shown more antibacterial activity than crude extract with minimal inhibitory concentration (MIC) values ranged from 5% to 2.5%. The amount of total flavonoid and antioxidant activity of Hawthorn fruits (Crataegus spp) in various concentration extracts and antioxidant activities of different concentration extracts were determined by radical scavenging by 2, 2-diphenyl-1-picrylhydrazyl (DPPH•). The output showed that the contents of flavonoid were found to be 0.386 mg quercet in equivalents (QUE/g). Dried extract displayed remarkable antioxidant activity according to (DPPH•) assays.

Keywords: Hawthorn fruits; DPPH; phytochemical; flavonoids; antibacterial

Received: July 28, 2021; Revised: August 26, 2021; Accepted: August 29, 2021; Prepublished online: September 3, 2021; Published: December 3, 2021  Show citation

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Omer, F.H., Abid, K.Y., & Mohammed, M.F. (2021). THE EFFECT OF FLAVONOIDS EXTRACTS FROM HAWTHORN (CRATAGUS OXYACANTHUS) AGAINST SOME GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA SPECIES. MMSL, 90(4), 158-164. doi: 10.31482/mmsl.2021.025
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