Behavioral tests were employed in the study of central effects of the selected neurotoxins mescaline, FAZ-4 and DSP-4 at stereotactical administration into three cerebral structures (ventriculus cerebri Iateralis, ncl. basalis Meynerti and nc. septi medialis).
The results have confirmed the assumed negative action with cholinergic and monoaminergic dysfunctions, manifested by a disorder in the recall from animal memory immediately after their administration and with latency of several weeks. Different effects of individual neurotoxins on animal behaviour were observed also in dependence on the structure of administration.

Keywords: Learning; Memory; Neurotoxins; Laboratory rats; Neurotransmitter’s deficits; Intracerebral administration