VZL 2004, 73(4):130-141
Primary Hypertension Pathogenesis
- Oddelenie vnútorných ochorení s JIS a EJ, LVN Košice, Slovenská republika
- Ústav fyziológie LF UPJŠ v Košiciach, Slovenská republika
Primárna hypertenzia je najčastejším chronickým ochorením v priemyslových krajinách. Patogenéza esenciálnej hypertenzie zostáva predbežne ešte nejasná. Pravdepodobne je to však multifaktoriálne ochorenie, dané rôznymi vplyvmi prostredia v interakcii s ešte nedeterminovanou genetickou predispozíciou. Určitá diagnóza je možná len po vylúčení sekundárnej príčiny.
Prítomnosť len malého percenta sekundárnych foriem hypertenzie v celkovej populácii chorých s hypertenziou nás oprávňuje hľadať organickú, hmatateľnú príčinu; podozrenie má korešpondovať so striktnou adherenciou k štandardným diagnostickým procedúram a liečebné dôsledky môžu vyplývať z očakávanej diagnózy.
Keywords: Primárna hypertenzia; Hemodynamika; Patogenéza
Primary hypertension is the most common chronic disease in industrialized countries. Primary hypertension pathogenesis still remains unclear. However, it is probably a "multifactorial" disease, influenced by various environmetal factors in interaction with a so far undetermined genetic predisposition. A particular diagnosis can only be made through the exclusion of a secondary cause.A small percentage of secondary forms of hypertension in the total population of patients with hypertension justifies us to search for an organically tangible cause of this disease. Any suspicion should correspond with the observance of a standard diagnostic procedure and the appropriate therapy should follow from the expected diagnosis.
Keywords: Primary hypertension; Haemodynamics; Pathogenesis
Received: April 4, 2003; Published: December 1, 2004 Show citation
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