VZL 2006, 75(1):1-6

Obesity and Microalbuminuria

Miroslav Brndiar1, Jaroslav Kačerovský1, Jiří Knížek2, Jan M. Horáček ORCID...1, Lucie Chadimová1, Ladislav Jebavý1
1 Univerzita obrany, katedra válečného vnitřního lékařství Fakulty vojenského zdravotnictví, Hradec Králové
2 Univerzita Karlova v Praze, Lékařská fakulta v Hradci Králové

V práci autoři prokázali vztah mezi obezitou a mikroalbuminurií. Hodnota mikroalbuminurie roste statisticky významně v závislosti na hodnotě BMI (výběrový koeficient mnohonásobné korelace R = 0,904). Zároveň byla zjištěna přímá závislost intenzity mikroalbuminurie na růstu glomerulární filtrace (R = 0,837). Obézní nemocný je tedy rizikový nejen z hlediska rozvoje aterosklerózy, ale také z hlediska nefropatologického.

Keywords: Mikroalbuminurie; Obezita; Body Mass Index; Ateroskleróza; Rizikové faktory

A significant correlation (R = 0,904) between body mass index and microalbuminuria in 21 patients was investigated. A similar correlation between microalbuminuria and glomerular filtration R = 0,837 was found as well. Obesity as an indifferent risk factor of nephropathologic events is presented.

Keywords: Microalbuminuria; Obesity; Body Mass Index; Atherosclerosis; Risk factors

Received: January 18, 2006; Published: March 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Brndiar, M., Kačerovský, J., Knížek, J., Horáček, J.M., Chadimová, L., & Jebavý, L. (2006). Obesity and Microalbuminuria. Vojenské Zdravotnické Listy, 75(1), 1-6
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. AGEWALL, S., et al. Does microalbuminuria predict cardiovascular events in nondiabetic men with treated hypertension? Amer. J. Hypertens., 1995, vol. 8, p. 337-342. Go to original source... Go to PubMed...
    2. AGEWALL, S., et al. Microalbuminuria, insulin sensitivity and haemostatic factors in non-diabetic treated hypertensive men. J. Intern. Med., 1995, vol. 237, p. 195-203. Go to original source... Go to PubMed...
    3. ALZAID, AA. Microalbuminuria in patients with NIDDM: an overview. Diabetes Care, 1996, vol. 19, p. 79-89. Go to original source... Go to PubMed...
    4. BRADNA, P. - PALIČKA, V. - PODZIMKOVÁ. J., aj. Proteinurie u nemocných systémovými chorobami pojiva. Rheumatologia, 1993, roč. 7, s. 79-83.
    5. CAMPBELL, FM. Microalbuminuria and nephropathy in insulin dependent diabetes mellitus. Arch. Dis. Child., 1995, vol. 73, p. 4-7. Go to original source... Go to PubMed...
    6. CASSUTO, D., et al. Microalbuminuria in obese subjects. Horm. Metab. Res., 1992, vol. 24, p. 302-303. Go to original source... Go to PubMed...
    7. COPPO, R., et al. Glomerular permselectivity to macromolecules in reflux nephropathy: microalbuminuria during acute hyperfiltration due to aminoacid infusion. Clin. Nephrol., 1993, vol. 40, p. 299-307. Go to PubMed...
    8. DECKERT, T., et al. Microalbunimuria Implications for micro - and macrovascular disease. Diabetes Care, 1992, vol. 15, p. 1181-1191. Go to original source... Go to PubMed...
    9. DRENICK, EJ., et al. Excessive mortality and causes of death in morbidity obese men. JAMA, 1980, vol. 243, p. 443-445. Go to original source...
    10. ERLEY, CM. - RISLER, T. Microalbuminuria in primary hypertension: is it a marker of glomerular damage? Nephrol. Dial. Transplant., 1994, vol. 9, p. 1713-1715. Go to PubMed...
    11. GOLDSZER, R., et al. Renal findings in obese humans (Abstract). Kidney Int., 1984, vol. 24, p. 165.
    12. GOSLING, P. Microalbuminuria: a marker of systemic disease. Brit. J. Hosp. Med., 1995, vol. 54, p. 285-290.
    13. HALLAB, M., et al. Comparison of reduction in microalbuminuria by enalapril and hydrochlorothiazide in normotensive patients with insulin dependent diabetes. Brit. Med. J., 1993, vol. 306, p. 175-182. Go to original source... Go to PubMed...
    14. HÁTLE, J. - LIKEŠ, J. A First Course in Probability Theory and Mathematical Statistics. Praha, SNTL, Bratislava, ALFA, 1972.
    15. HEBÁK, P. - HUSTOPECKÝ, J. Multidimensional Statistical Methods. Praha, SNTL, Bratislava, ALFA, 1987.
    16. HEBÁK, P. - HUSTOPECKÝ, J. Multidimensional Statistical Methods. Praha, SNTL, Bratislava, ALFA, 1987. 273 p.
    17. HINDMARSH, JT. Microalbuminuria. Clin. Lab. Med., 1988, vol. 8, p. 611-616. Go to original source... Go to PubMed...
    18. JENNETTE, JC. - CHARLES, L. - GRUBB, W. Glomerulomegaly and focal segmental glomerulosclerosis associated with obesity and sleep-apnoea syndrome. Amer. J. Kidney Dis., 1987, vol. 10, p. 470-472. Go to original source... Go to PubMed...
    19. KAČEROVSKÝ, J. - BRNDIAR, M. - TICHÝ, M. Mikroalbuminurie v současné klinické praxi. Voj. zdrav. Listy, 1997, roč. 66, č. 2, s. 29-32.
    20. KNÍŽEK, J. - ÖSTERREICHER, J. - MACELA, A. The probability in the Excel t-Test. Voj. zdrav. Listy, 2000, roč. 69, č. 5, s. 206-213.
    21. LOKKEGAARD. N. - HAUPTER, I. - KRISTENSEN, TB. Microalbuminuria in obesity. Scand. J. Urol. Nephrol., 1992, vol. 26, p. 275-278. Go to original source... Go to PubMed...
    22. MÁLKOVÁ, J. - KIMLOVÁ, I. - FENCLOVÁ, Z. Mikroalbuminurie v klidu a po zátěži v primární prevenci ischemické choroby srdeční. Prakt. Lék., 1991, roč. 71, s. 409-412.
    23. MELOUN, M. - MILITKÝ, J. Statistical Processing of Experimental Data. Praha, PLUS, 1994. 347 p.
    24. OSTERBY, R. Microalbuminuria in diabetes mellitus - is there a structural basis? Nephrol. Dial. Transplant., 1995, vol. 10, p. 12-14.
    25. PANAYIOTOU, BN. Microalbuminuria: pathogenesis, prognosis and management. J. Int. Med. Res., 1994, vol. 22, p. 181-201. Go to original source... Go to PubMed...
    26. PREBBLE, WE. Obesity: Observation on one thousand cases. Boston Med. Surg. J., 1923, vol. 188, p. 617-621. Go to original source...
    27. STEIJAERT, MMC. - GAAL, LF. van - LEEUW, IH. de: Microalbuminuria in human obesity. Role of body composition, hyperinsulinaemia and hyperglycaemia. Nutr. Metab. Cardiovasc. Dis., 1997, vol. 7, p. 285-291.
    28. VALENSI, P., et al. Microalbuminurie et hypertension artérielle chez les obeses. Arch. Mal. Coeur, 1992, vol. 85, p. 1193-1195.
    29. WARNKE, RA. - KEMPSON, RL. The nephrotic syndrome in massive obesity. Arch. Pathol. Lab. Med., 1978, vol. 102, p. 431-438. Go to PubMed...
    30. WEISINGER, JR. - KEMPSON, RL. - ELDRIDGE, FL. The nephrotic syndrome: A complication of massive obesity. Ann. Intern. Med., 1974, vol. 81, p. 440-447. Go to original source... Go to PubMed...
    31. WESSON, DE. - KURTZMAN, NA. - FROMMER, JP. Massive obesity and nephrotic proteinuria with a normal renal biopsy. Nephron, 1985, vol. 40, p. 235-237. Go to original source... Go to PubMed...

    Return to the content