MMSL 2012, 81(1):2-8 | DOI: 10.31482/mmsl.2012.001

CARBAMATE INSECTICIDES IN THE CZECH REPUBLIC: HEALTH AND ENVIRONMENTAL IMPACTSReview article

Vítězslav Vlček1, Miroslav Pohanka ORCID...2*
1 Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic
2 Center of Advanced Studies, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic

Carbamates neurotoxins are a group of compounds acting as pseudo-irreversible inhibitors of an enzyme acetylcholinesterase and butyrylcholinesterase. The compounds are well known as pesticides. Some of them, such as rivastigmine, pyridostigmine, and neostigmine, can be used as drugs for Myasthenia gravis or Alzheimer disease as well. The present review is aimed to summarize the basic facts about carbamate pesticides. Legislative aspects, e.g. law No. 326/2004 Coll., in the Czech Republic and examples of accidental exposures to carbamates in the country are provided, too. Other general provisions are determined by the EU, in particular by the Directive 91/414/EHS. The European legislative is discussed, too. Finally, examples of accidental exposures are introduced in the study.

Keywords: Acetylcholinesterase; Butyrylcholinesterase; Pyridostigmine; Pesticide toxicity; Persistence; Carbofuran

Received: January 19, 2012; Revised: February 12, 2012; Published: March 9, 2012  Show citation

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Vlček, V., & Pohanka, M. (2012). CARBAMATE INSECTICIDES IN THE CZECH REPUBLIC: HEALTH AND ENVIRONMENTAL IMPACTS. MMSL, 81(1), 2-8. doi: 10.31482/mmsl.2012.001
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