MMSL 2013, 82(2):63-68 | DOI: 10.31482/mmsl.2013.009
MICROREACTOR TECHNOLOGY IN WARFARE AGENT CHEMISTRYOriginal article
- 1 Federal Office for Civil Protection FOCP, SPIEZ LABORATORY, 3700 Spiez, Switzerland
- 2 Department of Chemistry, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland
Even though the use of microreactors for synthesising classical chemical warfare agents or other compounds scheduled in the CWC (Chemical Weapons Convention) has not been published to date, the new technology has attracted the attention of the organic chemistry group of SPIEZ LABORATORY. Studies of the group show that in a few areas and sectors of chemistry, microreactors can provide a good alternative to the batch procedure. In classic warfare chemistry however, the technology can bring no benefits, since many reactions pro-duce a solid and are thus entirely unsuitable for microreactors.
Keywords: Microreactor Technology; Microreactor-Systems; Warfare Agents; CWC
Received: January 17, 2013; Revised: February 22, 2013; Published: June 5, 2013 Show citation
References
- Rumi, L., Beitrag zur Grünen Chemie: Anwendung der Mikroreaktor Technologie und neuartiger heterogener Palladium(0)-Katalysatoren auf Grafitoxid-Basis, Doctoral Thesis, 2009, Faculty for Chemistry, Pharmacy and Earth Sciences at the Albert-Ludwigs University of Freiburg, Germany.
- Geyer, K., Fabrication and Use of Micro-reactors for Synthetic Organic Chemistry, Doctoral Thesis, 2009, ETH no. 18148, Swiss Federal Institute of Technology, Zurich, Switzerland.
- Kappe, C. O., Dallinger, D., Murphree, S. S., Practical Microwave Synthesis for Organic Chemists, WILEY-VCH (ed.), 2009.
Go to original source... - (a) Hessel, V., Novel Process Windows - Gate to Maximizing Process Intensification via Flow Chemistry, Chem. Eng. Technol, 2009, 32, 1655; (b) Geyer, K., Gustafson, T., Seeberger, P. H., Developing Con-tinous-Flow Microreactors as Tools for Synthetic Chemists, Synlett, 2009, 15, 2382; (c) Hartman, R. L., Jensen, K. F., Microchemical systems for continous-flow synthesis, Lab Chip, 2009, 9, 2495; (d) Mak, X. Y., Laurino, P., Seeberger, P. H., Asymmetric reactions in continous flow, Beilstein J. Org. Chem. 2009, 5 (19); (e) Baxendale, I. R., Ley, S. V., in New Avenues to Efficient Chemical Synthesis Emerging Technologies, ed. Seeberger, P. H., Blume, T., Springer, Berlin, Heidelberg, 2007, p. 151; (f) Ehrfeld, W., Hessel, V., Löwe, H., Microreactors : New Technology for Modern Chemistry, Wiley-VCH, Weinheim, 2000, pp.230-256; (g) Wirth, T. (ed.), Microreactors in Organic Synthesis and Catalysis, Wiley-VCH, Weinheim, 2008, 283 pages.
- Roberge, D. M., Ducry, L., Bieler, N., Cret-ton, P., Zimmermann, B., Microreactor Technology: A Revolution for the Fine Chemical and Pharmaceutical Industries ?, Chem. Eng. Technol., 2005, 3, 28. Go to original source...