MMSL 2013, 82(4):142-148 | DOI: 10.31482/mmsl.2013.023

MYCOPLASMA INFECTIONS IN HUMANSReview article

Radek Sleha ORCID...1,2*, Vanda Boštíková ORCID...1, Miloslav Salavec3, Pavel Boštík ORCID...4, Eva Slehová2, Rudolf Kukla2, Petra Mosio2, Markéta Vydržalová2, Jaroslava Mazurová2
1 Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove
2 Department of Biology and Biochemistry, Faculty of Chemical-Technology, University of Pardubice
3 Department of Dermatovenereology, Faculty of Medicine, Charles University, Hradec Kralove
4 Department of Infectious Diseases, Charles University Medical School and University Hospital, Hradec Kralove and Faculty of Military Health Sciences, University of Defence, Hradec Kralove

Members of the genus Mycoplasma are parasitic bacteria that are widespread in nature. Several Mycoplasma species are important causative agents of various infections of mucosal surfaces in humans, especially in the urogenital or respiratory tracts. Pathogenetic mechanisms of mycoplasmas are intensively studied.The "gold" standard of mycoplasma detection is cultivation, which is very difficult and time-consuming. The other options for identifying mycoplasmas include direct antigen detection or molecular-biology methods, such as polymerase chain reaction, DNA-hybridization and sequencing.Mycoplasmas are naturally resistant to beta-lactam antibiotics because of lack of cell wall. Tetracyclines or fluoroquinolones are regarded as the first choice in the treatment of mycoplasma infections. Several reports have documented resistance of mycoplasmas to macrolides worldwide.This report summarizes our current knowledge of laboratory diagnosis and treatment of mycoplasma infections.

Keywords: Mycoplasma; infections; antimicrobial susceptibility; detection

Received: July 9, 2013; Revised: October 30, 2013; Published: December 5, 2013  Show citation

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Sleha, R., Boštíková, V., Salavec, M., Boštík, P., Slehová, E., Kukla, R., ... Mazurová, J. (2013). MYCOPLASMA INFECTIONS IN HUMANS. MMSL, 82(4), 142-148. doi: 10.31482/mmsl.2013.023
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