Vojenské Zdravotnické Listy, 2010 (vol. 79), issue 3
Colour Supplement
VZL 2010, 79(3):I-IV 
Editorial
Kamil Kuča
VZL 2010, 79(3):89
Vaccination of the Czech Republic Army Soldiers Sent to Missions Abroad
Petr Dítě, Roman Chlíbek
VZL 2010, 79(3):90-95
The article deals with the problems of vaccination of the Czech Republic Army soldiers, who are sent to missions abroad. It gives the reasons why the vaccination is an integral part of every contingent. It deals with the scope of legislation on vaccination. The most frequently used vaccinations before departure on missions are described here, including a short characteristics of particular vaccines. Issues of vaccination organization and guidance of documentation are mentioned. The types of side reactions and contraindications are listed.
Is There Any Chance to Improve Quality of Life of These Seniors?
Jan Lužný, Kateřina Ivanová
VZL 2010, 79(3):96-104
The authors discuss an issue of demographic aging, heterogeneity of seniors, specific needs and questionable issues in seniors with mental disorders hospitalized at the Department of Gerontopsychiatry. The seniors with a psychiatric morbidity dependent on institutional care usually stand at the fringe interest of the society, even research does not pay a proper attention to them. From the point of financial costs, the gerontopsychiatry is incredibly underpaid area - there is a lack of money for both reconstruction and modernization of obsolescent gerontopsychiatric departments of mental homes. A guardian of the human rights has repeatedly warned about...
Immobilization of Acetylcholinesterase and a Construction of Biochemical Biosensor for Identification of Toxic Organophosphates
Miroslav Pohanka, Oto Drobík, Zuzana Křenková, Jana Žďárová Karasová, Jiří Cabal, Kamil Kuča
VZL 2010, 79(3):105-110
Biosensors are analytical devices based on tight junction of so-called biorecognition element and a physicochemical transducer. In this study, a screen printed sensor with platinum working electrode as the transducer and acetylcholinesterase as the biorecognition element were used. Acetylcholinesterase was immobilized in a different way including sol-gel technologies, immobilization on graphite nanofibers, precipitation with glutaraldehyde and interception into spherical graphite microparticles. Efficacy for given immobilization protocols was estimated, and practical impact of the study was discussed.
Testing of a Referential Method Based on Indoxylacetate as a Acetylcholinesterase Substrate for Identification of Reactivation Efficacy
Miroslav Pohanka, Martina Hrabinová, Jana Žďárová Karasová, Ondřej Holas, Kamil Kuča, Jiří Cabal
VZL 2010, 79(3):111-113
Biochemical evaluation of acetylcholinesterase activity is an important factor for selection and evaluation of drugs, such as oxime reactivators, which modulate acetylcholinesterase activity. A spontaneous reaction between an Ellman reagent and an oxime reactivator is the main disadvantage of currently available Ellman's method used for identification of cholinesterase activity. In this study, an alternative chromogen, substrate indoxylacetate is used. It is suitable for evaluation of acetylcholinesterase reactivation efficacy without oxime interference in vitro. The method was successfully examined for five standard oxime reactivators (HI-6, methoxime,...
Beta-Amino Acids and Their Natural Biologically Active Derivatives. III. Derivatives of Beta-Phenylalanine and Beta-Tyrosine
Jiří Patočka
VZL 2010, 79(3):114-118
Unlike proteinogenic α-amino acids that are constituents of all proteins and enzymes, which control the metabolism in living matter, β-amino acids are less abundant than their α-isomers. Mostly they occur as constituents of distinct natural products, such as peptides, cyclopeptides, depsipeptides, glycopeptides, alkaloids or terpenoids. Especially, bacteria, cyanobacteria, fungi, and plants often incorporate β-amino acids into their secondary metabolites. These serve as tools to secure their survival in competition with other organisms. Therefore, these compounds are often characterized by potent biological activities which are...
NATO Advanced Training Course - the Best Way of Training for Mass Casualty Situations
Leo Klein, Moshe Michaelson, Walter Kaffenberger, Gila Hyams
VZL 2010, 79(3):119-122
The NATO Advanced Training Course on training for mass casualty situations was held in cooperation with Traumacenter Rambam Hospital in Haifa, Israel from November 16-18, 2009. In total, 22 participants from 8 countries of the Partnership for Peace and Mediterranean Dialogue Programmes attended the course. The participants, divided into three groups, discussed and practised scenarios of mass casualty management in the area of pre-hospital care, hospital care and use of non-conventional weapons. The international team of instructors used the following teaching methods: general lectures, guided discussions, use of advanced multimedia tools, tabletop...
Cowpox - New Findings
Marie Vacková, Roman Chlíbek, Jan Smetana, Vanda Boštíková, Irena Hanovcová, Petra Matulková, Miroslav Špliňo
VZL 2010, 79(3):123-125
Recently, wild rodents have appeared to be a main reservoir of cowpox virus (e.g. Microtus sp.). Cowpox viruses can be transmitted to some pets and consequently people are infected by a direct contact. The entry of infection is usually the impaired skin. The occurrence of cowpox is sporadic. Recent cases have been reported primarily in children and adolescents.
Who Synthetised the First Organophosphorus Inhibitor of Acetylcholinesterase?
Jiří Patočka
VZL 2010, 79(3):126-128
The tetraethyl pyrophosphate (TEPP), the first synthetically prepared organophosphorus inhibitor of acetylcholinesterase, is put down to the French chemist Philippe de Clermont. Nevertheless, certain facts show that the first synthesis of TEPP was achieved by Clermont's colleague, likewise working in Adolphe Wurtz's laboratory in Paris. This person was a Russian student, Wladimir Petrovich Moschnine from Moscow. While Clermont was well known, nobody knew who Moschnine was. Due to young Portuguese researcher, Ana Carneiro, and Professor George A. Petroianu from the United Arab Emirates University, they managed to elucidated yet unknown history of organophosphate...
Book Review - Ramesh C. Gupta (ed.): Handbook of Toxicology of Chemical Warfare Agents. Amsterdam, Boston, 2009
Vladimír Měrka, Dušan Šimkovič
VZL 2010, 79(3):129