MMSL, 2016 (vol. 85), issue 1
HI-6 TREATMENT DOES NOT REACTIVATE SARIN INHIBITED ACETYLCHOLINESTERASE ACTIVITY IN DOG BRAIN WHEN ADMINISTERED IN HUMAN THERAPEUTICAL DOSE 30 MINUTES AFTER THE POISONINGOriginal article
Filip Caisberger, Ladislav Novotný, Petr Hájek, Jan Misík, Jiří Kassa, Jaroslav Pejchal
MMSL 2016, 85(1):2-7 | DOI: 10.31482/mmsl.2016.001 
Purpose: The aim of our study was to determine and compare the activity of acetylcholinesterase (AChE) in different parts of dog brain after the exposure to nerve agent sarin with or without HI-6 oxime treatment.Material and methods: Before intoxication, beagle dogs were intravenously anaesthetized and premedicated with atropine sulphate (0.01 mg/kg). Three experimental groups were established - control, sarin (0.03 mg/kg, intramuscularly, 5 min after anaesthesia onset), and sarin + HI-6 dichloride (11.4 mg/kg, intramuscularly, 30 min after sarin poisoning). Brain (amygdaloid body, head of caudate nucleus, somatosensory cortex, Amon's horn of hippocampus,...
TERRORISM - DEFINITIONS NEEDEDReview article
Hana Tomášková, Jitka Kühnová, Kamil Kuča
MMSL 2016, 85(1):8-12 | DOI: 10.31482/mmsl.2016.002
International terrorism is rightly regarded as one of the greatest threats to world security and stability. Terrorist attacks that have occurred in recent years around the world have highlighted the need for a comprehensive approach. Formulation of the problem is a prerequisite for successful work, but the main problem is that there is no single definition of terrorism. View on possible definitions and important concepts are mentioned in this article.
ORLISTAT AND PHENTERMINE IN WEIGHT LOSS IN SELECTED CZECH POPULATIONOriginal article
Vladimír Pavlík, Jana Fajfrová, Jan M. Horáček, Václav Šafka, Pavla Krutišová, Miroslav Urban, Peter Urban, Jana Gazdačková, Petr Navrátil
MMSL 2016, 85(1):13-18 | DOI: 10.31482/mmsl.2016.003
Aim: To describe effectiveness of orlistat and phentermine in soldiers of the Armed Forces of the Czech Republic.Methods: In ambulatory patients, some anthropometric and biochemical parameters were compared before administration with 120 mg of orlistat three times a day or 15 mg of phentermine once a day. The same parameters were compared after a three-month therapy. This group included 289 patients (238 males and 51 females) who were administered the same dose of orlistat or phentermine for the entire period of time.Results: Statistically significant weight loss in both genders, on average by 4.6 ± 4.2 kg in males and by 5.3 ± 4.3 kg in...
HUMULUS LUPULUS L. (HOPS) - A VALUABLE SOURCE OF COMPOUNDS WITH BIOACTIVE EFFECTS FOR FUTURE THERAPIESReview article
Jana Olšovská, Vanda Boštíková, Martin Dušek, Vladimíra Jandovská, Kateřina Bogdanová, Pavel Čermák, Pavel Boštík, Alexandr Mikyska, Milan Kolář
MMSL 2016, 85(1):19-30 | DOI: 10.31482/mmsl.2016.004
Hops are a well-known source of resins, essential oils and polyphenolic substances, such as proanthocyanidins or prenylflavonoids with significant representatives of xanthohumol, isoxanthohumol, and 8-prenylnaringenine, and represent an essential ingredient in beer production. Recently, however, many additional bioactive effects of hop compounds have been investigated.A systematic review of the structure-function relationship between the individual hop-derived compounds and their bio-activity has been lacking. In this review we summarize some recent findings in this area from reports from our as well as other studies. It shows multiple bio-medical...
CARDIAC MULTIMARKER TESTING IN NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHYOriginal article
Radek Pudil, Martina Vašatová, Alena Myslivcová Fučíková, Helena Řehulková, Pavel Řehulka, Vladimír Palička, Jiří Stulík
MMSL 2016, 85(1):31-38 | DOI: 10.31482/mmsl.2016.005
The natural history of hypertrophic cardiomyopathy (HCM) varies from an asymptomatic and benign clinical course to sudden premature death. Therefore, the new markers are searched with the aim to detect risk patients and improve their prognosis. The aim of this study was to test a cardiac multimarker testing strategy in detection of initial structural changes in patients with nonobstructive hypertrophic cardiomyopathy (HCM). In the group of 47 patients with nonobstructive HCM (58.4 ± 12.4 years, 12 emales) the mean left ventricle mass was 344.8 ± 129.9 g, the mean left ventricle mass index was 171.4 ± 60.2 g.m-2. We observed...
SYRIA CONFLICT AND CHEMICAL WEAPONS: WHAT IS THE REALITY?Review article
Jiří Patočka
MMSL 2016, 85(1):39-43 | DOI: 10.31482/mmsl.2016.006
The Syrian civil war is a shameful matter for the contemporary world. It is full of suffering for the civilian population and is one of the causes of the current huge migration of Syrian people in Europe. Suffering of people affected by the war is still escalating due to use of banned chemical weapons. The entire civilized world is appalled by the atrocities of the Syrian civil war.
Professor S.W.A. GUNN, MD, MS, FRCSC, FRCSI (Hon), DSc (Hon), dr. h. c. A 90th BIRTHDAY TRIBUTELetter to the editor
Leo Klein
MMSL 2016, 85(1):44-46
Geneva, Switzerland, celebrated a most remarkable 90th birthday jubilee. A highly respected Canadian surgeon who enjoys excellent mental and physical condition, and continues to perform the scientific and organizational work for which he has long been recognized throughout the world. A pioneer of medical emergency systems, Professor Gunn has contributed greatly to the emergence and evolution of Disaster Medicine, Humanitarian Medicine, and the expansion of surgical fields in developing and "third world" countries. He worked closely with officials for many countries and has continued this collaboration with Czech healthcare and medical educational...
WORLD CBRN & MEDICAL CONGRESS - 2016Announcement
Jan Heřmánek
MMSL 2016, 85(1):47
The World CBRN & Medical Congress (19.-21. October 2016) is divided into four thematic sessionsSession AStrategic and Comprehensive CBRN Defence - CBRN Protection, WMD/CBRN ThreatsSession BWMD Disablement, BMD (Ballistic Missiles Defence), Cyber DefenceSession CCivil-Military Cooperation on CBRN DefenceSession DR&D, CBRN Medical Countermeasures, Force Health Protection (FHP)
16th CONFERENCE ON MILITARY MEDICINEAnnouncement
Leo Klein
MMSL 2016, 85(1):48
Main topic: Military Health, Care and Support, Results of Medical/Surgical Treatment Procedures and Research, Varia, Poster Section.