MMSL, 2016 (vol. 85), issue 3
ZIKA VIRUS - A REVIEWReview article
Vanda Boštíková, Kamil Kuča, Pavel Blažek, Radek Sleha, Marketa Pasdiorová, Jan Marek, Hana Střítecká, Vladimír Hytych, Pavel Boštík
MMSL 2016, 85(3):94-103 | DOI: 10.31482/mmsl.2016.018 
In February 2016, the World Health Organization (WHO) declared the current Zika outbreak a Public Health Emergency of international concern. The Zika virus disease is caused by a virus (family Flaviviridae) transmitted by Aedes spp. mosquitoes. People with the Zika virus disease usually have symptoms that can include a low-grade fever, maculopapular rash, conjunctivitis, arthralgia, malaise, headache and retro-ocular headaches. Neurological and autoimmune complications have been described during the outbreaks in Polynesia and recently in Brazil. There are no licensed medical countermeasures - vaccines, therapies or preventive drugs available...
EXPRESSION OF p21 AND EXPRESSION AND ACTIVATION OF MAPK REGULATED TRANSCRIPTION FACTORS IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN RATS AFTER WHOLE-BODY γ-RADIATION AND ITS USE IN BIODOSIMETRYOriginal article
Jaroslav Pejchal, Šárka Průchová, Klára Kubelková, Aleš Tichý, Jiřina Vávrová
MMSL 2016, 85(3):104-110 | DOI: 10.31482/mmsl.2016.019
The aim of our study was to examine the in vivo expression of p21 and expression and activation of ATF-2, c-Myc, and CREB in rat peripheral blood mononuclear cells (PBMC) after whole body γ-irradiation and to assess its contribution to biodosimetry. For Western blot experiments, male Wistar rats were whole-body irradiated by a single dose of 0, 0.5, 1, 3, and 5 Gy (60Co, 1 m, 0.7 Gy/min). As a positive control, leukaemic MOLT-4 cells were used. For ELISA experiments, male Wistar rats were whole-body irradiated by a single dose of 0, 1, 2, 3, 4, and 5 Gy (60Co, 1 m, 0.6 Gy/min). Blood samples were taken 4 h after the irradiation...
FECAL MICROBIOTA THERAPY AND ITS POTENTIAL IN MEDICAL PRACTICEReview article
Kateřina Hašková, Markéta Dyrhonová, Vanda Boštíková
MMSL 2016, 85(3):111-120 | DOI: 10.31482/mmsl.2016.020
Fecal microbiota therapy is going through its renaissance period. Even in ancient China, stool and its derivats were used for therapy of various diseases. Now thanks to new molecular methods a new knowledge about the intestinal microbiome and its interference with the human physiology, this method can be used for concrete therapy of disease.
HISTORY AND WORK OF THE DEPARTMENT OF MILITARY INTERNAL MEDICINEReview article
Jaroslav Kačerovský, Ladislav Jebavý, Jan M. Horáček
MMSL 2016, 85(3):121-129
The purpose of this work is to give a brief overview on history and main directions of work at the Department of Military Internal Medicine (DMIM). Chiefs (commanders) of the department are presented in chronological order together with tasks they had to deal with during a given period of time. A close cooperation of the DMIM with civilian hospital departments is pointed out, mainly in the areas of therapeutic and preventive care together with education. A departmental contribution to the development of the Military Medical Service is specified in detail, particularly surgical and non-surgical casualties support.
THE MYSTERY OF GULF WAR SYNDROME PERSISTSLetter to the editor
Jiří Patočka
MMSL 2016, 85(3):130-131 | DOI: 10.31482/mmsl.2016.022
Gulf War Syndrome (GWS), also known as Gulf War Illness (GWI), is a long-term multi-symptom disorder which was described in military veterans and civilian workers who were employed in the first Gulf War (1990-1991). Out of approximately 700 000 soldiers who served in Operation Desert Storm (ODS), one-fourth to one-third (25-32%) of them reported symptoms corresponding to GWS. Medically unexplained symptoms have been reported among both civilians and military personnel involved in the combat. A wide range of acute and chronic symptoms have been linked to it, including fatigue, muscle pain, cognitive problems, rashes and diarrhea. Twenty-five years after...
16th CONFERENCE ON MILITARY MEDICINEAnnouncement
Leo Klein
MMSL 2016, 85(3):132
Topic: Current and Future Tasks of the Czech Military Medical Service; Refugees Crisis and Possible Health Care Risks; Prevention, Diagnostics and Treatment in Military Health Care System; Varia; Poster Section
8th SINGAPORE INTERNATIONAL SYMPOSIUM ON PROTECTION AGAINST TOXIC SUBSTANCES, 21-23 MARCH 2017Announcement
Weng Keong
MMSL 2016, 85(3):133-136
The 8th Singapore International Symposium for Protection Against Toxic Substances (SISPAT) is a technical forum that aims to share the latest knowledge and technology with regards to defence against unconventional threats amongst scientists and operations managers (military and public health) from the academia, government and other relevant industries. Asymmetrical threats posed by the use of unconventional agents transcend international boundaries and is constantly evolving to circumvent existing defence measures. Henceforth, defence measures against CBRN threats must leverage on bilateral and multi-lateral cooperation to remain effective....