MMSL 2001, 70(S2):70

REPRODUCTION TOXICITY SCREENING TEST OF THE VULM 1457 SUBSTANCE

Irina Sadloňová1, Eduard Ujházy2, Michal Dubovický2, Eva Flaškárová1
1 VULM, a.S. - Drug Researche Institute, Modra, Slovak Republic
2 Institute of Experimental Pharmacology, SAS, Bratislava, Slovak Republic

The OECD 421 (1995) Reproduction/Development Toxicity Screening Test was used in preclinical screening of toxicity of the VULM 1457 original hypolipidemic from the group of ACAT inhibitors. The purpose of the test was to collect information on the effect of the substance on basic reproductive performance of male and female rats, and, in case of positive toxicity findings, to establish the region of adverse effects.

Keywords: Toxicology; screening; vulm 1457

Published: December 2, 2001  Show citation

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Sadloňová, I., Ujházy, E., Dubovický, M., & Flaškárová, E. (2001). REPRODUCTION TOXICITY SCREENING TEST OF THE VULM 1457 SUBSTANCE. Vojenské Zdravotnické Listy, 70(Suppl.2), 70
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