VZL 2009, 78(2):41-47

Group G Streptococci

Petra Lysková
Univerzita Pardubice, katedra biologických a biochemických věd, Pardubice

Beta-hemolytické streptokoky se skupinovým antigenem G patří mezi podmíněně patogenní bakterie, které se mohou vyskytovat na kůži, sliznicích nosohltanu, gastrointestinálního a urogenitálního traktu lidí i zvířat. V posledních letech jsou však stále častěji potvrzovány jako původci různých, převážně akutních infekcí (endokarditidy, artritidy, meningitidy, faryngitidy a sepse). Z hlediska symptomatologie jsou shodné s infekcemi způsobenými S. pyogenes. U streptokoků se skupinovým antigenem G humánní provenience byly zjištěny některé faktory virulence jako M-protein, streptokináza, streptolyziny O a S, C5a peptidáza a pouzdro z kyseliny hyaluronové shodné se S. pyogenes. Nejčastěji izolovaným druhem ze zvířat je S. canis, z člověka zejména S. dysgalactiae ssp. equisimilis a skupina S. anginosus.

Keywords: Streptokoky se skupinovým antigenem G; Infekce; Faktory virulence; Terapie

Group G streptococci (GGS) are commonly regarded as commensals because they are often found in association with the normal flora of human and animal pharynx, skin, gastrointestinal and urogenital tract. In recent years, they have been reported with increasing frequency as a cause of variety of human infections, such as endocarditis, arthritis, meningitis, pharyngitis and sepsis. GGS infections have manifestinations similar to those caused by S. pyogenes. They express several virulence determinants initially identified in S. pyogenes, such as M protein, streptokinase, streptolysins O and S, C5a peptidase and hyaluronic acid capsule. The human isolates of beta-haemolytic GGS include the anginosus group and S. dysgalactiae ssp. equisimilis. S. canis is important animal pathogen.

Keywords: Group G streptococci; Infections; Virulence factors; Therapy

Received: January 15, 2009; Published: June 1, 2009  Show citation

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Lysková, P. (2009). Group G Streptococci. Vojenské Zdravotnické Listy78(2), 41-47
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