MMSL 2019, 88(3):98-105 | DOI: 10.31482/mmsl.2019.006

PERFLUOROISOBUTENE: POISONOUS CHOKING GASReview article

Jiri Patocka ORCID...1,2
1 Institute of Radiology, Toxicology and Civil Protection, Faculty of Health and Social Studies, University of South Bohemia České Budějovice, České Budějovice, Czech Republic
2 Biomedical Research Centre, University Hospital, Hradec Králové, Czech Republic

Perfluoroisobutene (PFIB) is a colorless toxic gas which can be absorbed into the body by inhalation. The substance irritates the respiratory tract and may be used as a potential chemical warfare agent.  Inhalation exposure may cause severe symptoms of pulmonary edema associated with wheezing, difficulty in breathing and sputum expectoration. A bluish skin color is also observed. Initially, cough and chest pain may occur. However, severe symptoms of pulmonary edema may be delayed for several hours before a rapid deterioration of health occurs. Excessive exposure may cause death.

Keywords: perfluoroisobutene; PFIB; irritant gas; acute lung injury; chemical warfare agent; toxicology

Received: February 25, 2019; Accepted: April 11, 2019; Prepublished online: April 26, 2019; Published: September 6, 2019  Show citation

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Patocka, J. (2019). PERFLUOROISOBUTENE: POISONOUS CHOKING GAS. MMSL, 88(3), 98-105. doi: 10.31482/mmsl.2019.006
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