MMSL 2024, 93(1):112-119 | DOI: 10.31482/mmsl.2023.006

CORRELATION BETWEEN COVID-19 SYMPTOMS AND CERTAIN PHYSIOLOGICAL AND BODY COMPOSITION PARAMETERS RELATED TO OBESITY AND OVERWEIGHTOriginal article

Attila Novák ORCID...1,2*, Szabolcs Szalánczi1, Beatrix Hornyák1, Zsófia Rázsó ORCID...3, Andrea Sótér4, Csaba Nyakas ORCID...2,5
1 Hungarian Defence Forces Medical Center, Department of Health Promotion, Budapest, Dózsa György út 112-114, 1068
2 Doctoral School of Health Sciences Semmelweis University, Budapest Üllői u. 26 Hungary 1085
3 NATO Centre of Excellence for Military Medicine, H-1555 Budapest, POB 66. Hungary
4 Hungarian Defence Forces Medical Center Command, Budapest, Róbert Károly körút 44, 1134
5 University of Physical Education, Budapest, Alkotás u. 42-48, 1123

Introduction: The high Body Mass Index and high body fat percentage are mentioned as factors influencing the severity of the course of COVID-19 disease. Our aim was to examine, in relation to their symptoms, the measured and estimated parameters of those included in the lifestyle program established by the armed forces suffering from mild to moderate COVID-19 disease.Sample and Methods: The average age of the examined sample (n=18) was 45.2 years. The average body weight for women was (n=8) 78.5 kg, for men 106.2 kg, the average body fat percentage for women was 40.6% and for men 30.6%. The instruments used for the examination were a BIA 500 (800/µA, 50 kHz), an Omron BF 511 body composition monitor, an ECG Cardioscan monitor, and a DYNA-19 hand grip dynamometer. We applied a two-sample T-test in the examination. Differences with p < 0.05 were considered statistically. Statistical calculations were performed in R environment with R-Studio program.

Results: The higher phase angle was characteristic at lower (p=0.04) and shorter (p=0.05) body temperatures. Higher body fat percentages were observed in the case of prolonged coughing (p=0.04). Lower cardiac function values were associated with higher fever (p=0.05) and difficulty in breathing (p=0.02), while higher cardiac stress percentage was associated with the appearance of chest pain (p=0.02) and higher fever (p=0.04).

Conclusion: It was not the location of adipose tissue but the magnitude of its amount that was related to the symptoms of mild to moderate COVID-19 in our sample, in contrast to several international observations.

Keywords: Military health; COVID-19; Health behaviour; Body composition

Received: August 16, 2022; Revised: February 6, 2023; Accepted: February 14, 2023; Prepublished online: February 24, 2023; Published: March 1, 2024  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Novák, A., Szalánczi, S., Hornyák, B., Rázsó, Z., Sótér, A., & Nyakas, C. (2024). CORRELATION BETWEEN COVID-19 SYMPTOMS AND CERTAIN PHYSIOLOGICAL AND BODY COMPOSITION PARAMETERS RELATED TO OBESITY AND OVERWEIGHT. MMSL, 93(1), 112-119. doi: 10.31482/mmsl.2023.006
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Ryan DH, Ravussin E, Heymsfield S. COVID 19 and the patient with obesity - the editors speak out. Obesity. 2020;28(5):847. doi: 10.1002/oby.22808. Go to original source... Go to PubMed...
    2. Grasselli G, Zangrillo A, Zanella A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the lombardy region, Italy. JAMA. 2020;323(16):1574-1581. doi: 10.1001/jama.2020.5394. Go to original source... Go to PubMed...
    3. Moser JS, Galindo-Fraga A, Ortiz-Hernandez AA, et al. Underweight, overweight, and obesity as independent risk factors for hospitalization in adults and children from influenza and other respiratory viruses. Influenza Other Respir Viruses. 2019;13(1):3-9. Go to original source... Go to PubMed...
    4. Garg S, Kim L, Whitaker M, et al. Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2. MMWR Morb Mortal Wkly Rep. 2020;69(15):458-464. Go to original source... Go to PubMed...
    5. Simonnet A, Chetboun M, Poissy J, et al. High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation. Obesity. 2020;28(7):1195-1199. doi: 10.1002/oby.22831. Go to original source... Go to PubMed...
    6. Lighter J, Phillips M, Hochman S, et al. Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission. Clin Infect Dis. 2020:ciaa415. doi: 10.1093/cid/ciaa415 Go to original source... Go to PubMed...
    7. Luzi L, Radaelli MG. Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic. Acta Diabetol. 2020;57(6):759-764. doi: 10.1007/s00592-020-01522-8. Go to original source... Go to PubMed...
    8. Dietz W, Santos-Burgoa C. Obesity and its implications for COVID-19 mortality. Obesity. 2020;28(6):1005. doi: 10.1002/oby.22818. Go to original source... Go to PubMed...
    9. Jia X, Yin C, Lu S, et al. Two things about COVID-19 might need attention. Preprints. 2020:2020020315. doi: 10.20944/preprints202002.0315.v1. 23-2-0020. Ref Type: Internet Communication. Go to original source...
    10. Honce R, Karlsson EA, Wohlgemuth N, et al. Obesity-related microenvironment promotes emergence of virulent influenza Virus strains. mBio. 2020;11(2) Go to original source... Go to PubMed...
    11. Maier HE, Lopez R, Sanchez N, et al. Obesity increases the duration of influenza A Virus shedding in adults. J Infect Dis. 2018;218(9):1378-1382. Go to original source... Go to PubMed...
    12. Sattar N, McInnes IB, McMurray JJV. Obesity a risk factor for severe COVID-19 infection: multiple potential mechanisms. Circulation. 2020;142(1):4-6. doi: 10.1161/CIRCULATIONAHA.120.047659. Go to original source... Go to PubMed...
    13. Kanter R, Caballero B. Global gender disparities in obesity: a review. Adv Nutr. 2012;3(4):491-498. Go to original source... Go to PubMed...
    14. Tsuzura H, Genda T, Sato S, et al. Association of visceral obesity with high viral load and histological findings in elderly patients with genotype 1 chronic hepatitis C. Intern Med. 2013;52(15):1665-1673. Go to original source... Go to PubMed...
    15. Thibault R, Makhlouf AM, Mulliez A, et al. Fat-free mass at admission predicts 28-day mortality in intensive care unit patients: the international prospective observational study Phase Angle Project. Intensive Care Med. 2016;42(9):1445-1453. Go to original source... Go to PubMed...
    16. Weijs PJ, Looijaard WG, Dekker IM, et al. Low skeletal muscle area is a risk factor for mortality in mechanically ventilated critically ill patients. Crit Care. 2014;18(2):R12. Go to original source... Go to PubMed...
    17. Decree 10/2015 (30 July 2015) of the Ministry of Defence on Health, Psychological and Physical Fitness for Military Service and the Review Procedure. 10307. Hungarian Official Gazette, No 111. https://net.jogtar.hu/jogszabaly?docid=a1500010.hm
    18. Lee Y, Kwon O, Shin CS, et al. Use of bioelectrical impedance analysis for the assessment of nutritional status in critically ill patients. Clin Nutr Res. 2015;4(1):32-40. Go to original source...
    19. Stapel SN, Looijaard WGPM, Dekker IM, et al. Bioelectrical impedance analysis-derived phase angle at admission as a predictor of 90-day mortality in intensive care patients. Eur J Clin Nutr. 2018;72(7):1019-1025. Go to original source... Go to PubMed...
    20. Norman K, Stobäus N, Pirlich M, et al. Bioelectrical phase angle and impedance vector analysis--clinical relevance and applicability of impedance parameters. Clin Nutr. 2012;31(6):854-861. Go to original source... Go to PubMed...
    21. Kulcsar KA, Coleman CM, Beck SE, et al. Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection. JCI Insight 2019;4(20). Go to original source...
    22. Alves EAS, Salazar TCDN, Silvino VO, et al. Association between phase angle and adverse clinical outcomes in hospitalized patients with COVID-19: A systematic review. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2022;37(5), 1105-1116. https://doi.org/10.1002/ncp.10901 Go to original source... Go to PubMed...
    23. Cornejo-Pareja I, Vegas-Aguilar IM, García-Almeida JM, et al. Phase angle and standardized phase angle from bioelectrical impedance measurements as a prognostic factor for mortality at 90 days in patients with COVID-19: A longitudinal cohort study. Clinical nutrition (Edinburgh,Scotland),2022;41(12):3106-3114. https://doi.org/10.1016/j.clnu.2021.02.017 Go to original source... Go to PubMed...
    24. González-Islas D, Sánchez-Moreno C, Orea-Tejeda A, et al. Body composition and risk factors associated with sarcopenia in post-COVID patients after moderate or severe COVID-19 infections. BMC pulmonary medicine. 2022;22(1):223. https://doi.org/10.1186/s12890-022-02014-x Go to original source... Go to PubMed...
    25. Moonen H, van Zanten F, Driessen L, et al. Association of bioelectric impedance analysis body composition and disease severity in COVID-19 hospital ward and ICU patients: The BIAC-19 study. Clinical nutrition (Edinburgh, Scotland). 2021;40(4):2328-2336. https://doi.org/10.1016/j.clnu.2020.10.023 Go to original source... Go to PubMed...
    26. Severin R, Arena R, Lavie CJ, et al. Respiratory muscle performance screening for infectious disease management following COVID-19: a highly pressurized situation. Am J Med. 2020;133(9):1025e32. Go to original source... Go to PubMed...
    27. Sood A. Altered resting and exercise respiratory physiology in obesity. Clin Chest Med 2009;30(3):445e54. vii. Go to original source... Go to PubMed...
    28. Moon TS, Fox PE, Somasundaram A, et al. The influence of morbid obesity on difficult intubation and difficult mask ventilation. J Anesth 2019;33(1):96e102. Go to original source... Go to PubMed...
    29. Gao YD, Ding M, Dong X, et al. Risk factors for severe and critically ill COVID-19 patients: A review. Allergy, 2021;76(2):428-455. https://doi.org/10.1111/all.14657 Go to original source... Go to PubMed...
    30. Soeroto AY, Soetedjo NN, Purwiga A, et al. Effect of increased BMI and obesity on the outcome of COVID-19 adult patients: A systematic review and meta-analysis. Diabetes & metabolic syndrome. 2020;14(6):1897-1904. https://doi.org/10.1016/j.dsx.2020.09.029ű Go to original source... Go to PubMed...
    31. Bretz Károly János. Human effort, coordination and tremor measurement technique 2010 Budapest, Doctoral (PhD) thesis Budapest University of Technology and Economics [Hungarian]
    32. Mol M, Strous M, van Osch F, et al. Heart-rate-variability (HRV), predicts outcomes in COVID-19. PloS one, 2021;16(10):e0258841. https://doi.org/10.1371/journal.pone.0258841 Go to original source... Go to PubMed...

    Return to the content