Vojenské Zdravotnické Listy, 2003 (vol. 72), issue 5
HEART DAMAGE CAUSED BY EXTERNAL TOXIC AGENTS
Jan Horáček, Radek Pudil, Ladislav Jebavý
VZL 2003, 72(5):197-202 
Cardiotoxicity or toxic heart damage can be caused by external or internal toxic agents. A pathogenic I agent can damage single heart structures; most frequently, the myocardium is affected.The authors review the most frequent external toxic agents damaging the heart. These include: biological toxins, chemical toxins from the workplace and environment, radiation, addictive substances (alcohol and drugs), medicaments and, last but not least, cytostatics. Toxic heart damage is not very common, however; because of its possible fatal complications it represents a relevant and current problem.
MYCOTOXINS AS BIOLOGICAL WARFARE AGENTS
Miroslav Brndiar, Jaroslav Kačerovský, František Malíř, Alena Vosečková, Ladislav Jebavý
VZL 2003, 72(5):203-207
The authors point out in their study the basic general risks of biological terrorism. They analyse in detail the nephrotoxicity of mycotoxin ochratoxin A (OTA). The OTA plasmatic level has been examined in a large group of healthy individuals. The OTA levels have been compared in a group of patients with chronic renal insufliciency. A significantly higher OTA level has been proven in patients with chronic renal insuficiency. The possibility of whether OTA retention in chronic renal insuficiency is not an additional accelerating progression factor of basic nephropathy which leads to chronic renal failure has been considered.
THE CONTRIBUTION TO DIFFERENTIAL DIAGNOSIS OF THE MEDIASTINUM TUMORS
Ladislav Slováček, Martin Blažek
VZL 2003, 72(5):208-212
The authors prepared for this presentation a case history of a patient with a rare thymoma tumor. The case report points out the differential diagnosis of the mediastinum tumors.
THE INCIDENCE OF ATHEROGENESIS RISK FACTORS IN OFFICERS AT THE MINISTRY OF DEFENCE AND AT THE CZECH ARMY GENERAL STAFF (1999-2001)
Martin Hříbek, Ladislav Krajči, Jozef Klein, Tomáš Novosad, Chrisula Štěpánková
VZL 2003, 72(5):213-216
In a given group of officers we have investigated the incidence and prevalence of atherogenesis risk factorsduring annual medical examinations from 1999 to 2001.
BODY HEIGHT AND WEIGHT IN YOUNG MEN AGED 18-25 IN THE SECOND HALF OF THE 20th CENTURY
Daniel Jirkovský
VZL 2003, 72(5):217-220
This article presents the partial results of an anthropometrical measurement of basic duty soldiers from 2000 to 2001 in the Velká Hleďseb garrison. In the text, tables and graphs, two somatic signs are characterized — body height and weight. In the timeline from 1955 an acceleration in the growth of the average body height and weight in young men aged 18—25, and a slowing down of the secular trend from the second half of the I980s were described.
THE GENOTOXIC RISK OF "GEOCKERMAN’S THERAPY" FOR PSORIASIS (PILOT STUDY)
Lenka Borská, Jindra Šmejkalová, Zdeněk Fiala, Květoslava Hamáková, Jiřina Baudyšová
VZL 2003, 72(5):221-222
Goeckerman’s method of therapy for psoriasis includes combined exposure to therapeutic tar and UV-B radiation. In this pilot study (13 patients) the level of genotoxic risk of therapy was evaluated by using the chromosomal aberration of the peripheral lymphocytes. This study suggested the presence of an increased genotoxic risk in the therapy.
AN EVALUATION OF THE RISKS OF THE NON-AUDITORY EFFECTS OF ROAD TRAFFIC NOISE
Ľubica Sobotová, Jana Jurkovičová, Zuzana Štefániková, Ludmila Ševčíková, Ľubica Ághová
VZL 2003, 72(5):223-225
Noise presently ranks as one of the most widespread occupational and environmental hazards. Road traffic noise has become in the last decades a frequent, unavoidable and continuously increasing environmental factor with auditory and non-auditory health effects. The objectives of the present study were to evaluate the influence of road traffic noise on some non-auditory health effect indicators (annoyance, systolic and diastolic blood pressures, and the cardiovascular risk score), to investigate the associations among them and to calculate some of the non-auditory health effect risks of road traffic noise. Our sample included the group exposed to road...
HEALTH EFFECTS OF POLYPHENOLS FROM THE STANDPOINT OF THEIR INTAKE AND BIOAVAILABILITY
Zdeněk Zloch
VZL 2003, 72(5):226-229
Plant phenolic substances and phenolic substances in food have continually been a subject of scientific research. Thanks to this research effort, knowledge concerning the chemical structure and occurrence of these compounds in food has become more accurate. Properties and effects other than the antioxidative ones have been confirmed in relation to the phenolics. Some of their biological activities have been discovered (for instance the blocking, initiation and progression processes in carcinogenesis). There is a chance to evalute them in cancer research and to apply them in the therapy and prevention of this disease. The traditional epidemiological...
4. KONFERENCE ODBORNÉ SPOLEČNOSTI VOJENSKÝCH LÉKAŘŮ A FARMACEUTŮ ČLS JEP
Josef Fusek
VZL 2003, 72(5):229
THE INFLUENCE OF KETAMINE AND ITS COMBINATION WITH MEDETOMIDINE ADMINISTERED BY INHALATION ON THE BEHAVIOUR AND NEUROLOGICAL FUNCTION OF RATS
Ladislav Hess, Josef Vachek, Lucie Ševelová, Gabriela Krejčová, Jitka Schreiberová, Josef Fusek
VZL 2003, 72(5):230-235
The influence of the dissociative anaesthetic ketamine and its combination with the alpha 2 agonist medetomidine administered nasaly and by inhalation on behaviour and neurologicalfunctions was demonstrated in experiments in rats. Animals inhaled the drugs in two whole-body glass chambers, each having a volume of 410 ml. The anaesthetic aerosol was generated by a nebuliser based on a mobile form of the Henderson apparatus. The particle volume concentration of the aerosol generated was measured by a Royco 225 particle counter. The theoretical ketamine concentration during two and ten minute exposures was 3.57 mg/l of inhaled air. During the ketamine...
POSSIBILITIES OF 1-(4-HYDROXYIMINOMETHYLPYRIDINIUM)-3(4-CARBAMOYLPYRIDINIUM)-PROPANE DIBROMIDE
Jiří Bielavský, Kamil Kuča, Jiří Cabal, Marcela Bielavská
VZL 2003, 72(5):236-238
Synthesis and in vitro testing of a new potential acetylcholinesterase (AChE) reactivator — I —(4-hydroxyimi-nomethylpyridinium)-3-(4-carbamoylpyridinium)-propane dibromide have been carried out. Its reactivation efficacy to sarin-inhibited AChE and VX is comparable to that of the standard reactivator HI-ó. Its reactivation efficacy to sarin is better than its efficacy to oxime HI-6 and its reactivation efficacy to cyclosarin is insufficient.
THE BYSTANDER EFFECT OF IONIZING RADIATION II: REACTIONS OF BYSTANDER CELLS AT THE GENE AND PROTEIN LEVELS
Jan Österreicher, Jürgen Vogt, Tilman Butz, Leoš Navrátil, Aleš Macela
VZL 2003, 72(5):239-243
This study presents briefly the bystander effect mechanisms in bystander cells and tissues at the genetic and protein level. The possible actions Of overexpressed molecules in bystander cells are explained step by step, i.e. RAD 51, TP 53, CDKNIA (p21, WAF-1), Cyclin B1, p34 (cdc 2), beta 1 integrin, and interleukin 1 alpha actions in bystander mechanisms.
DISABLED SOLDIERS’ HOSPICES IN BOHEMIA
František Dohnal
VZL 2003, 72(5):244-249
The beginning of care for disabled and sick Soldiers in the Habsburg monarchy goes back to the early 18th century. Earl Peter Strozzi was the originator of this social care. His name is also connected with the foundation for establishing and running the disabled Soldiers’ hospice for retired soldiers. A large disabled Soldiers, hospice was established and opened in Prague in 1735. In 1935 a new modern disabled soldiers’ hospice was set up in Hořice v Podkrkonoší. Apart from a break during the war, it was used till 1964. Later on, this type of care was carried out by social welfare institutions.
FOOD AS A POTENTIAL WAY OF BIOTERRORISTIC ACTIVITY
Jerzy Bertrandt, Eugeniusz Rozmysl
VZL 2003, 72(5):250-252
This work describes the possibilities of using food as an element of bioterrorist activity. At the present time the infection or contamination of food products is considered to be easier than the use of aerosols in bioterrorist attacks. Terrorists can use food in their attacks which can cause casualties but can also provoke fear and panic, a reduction in confidence or even distrust of the authorities. The efiect of bioterrorist activity on food producers can cause a constant reduction of production and sales which can lead to significant material losses.