MMSL 2015, 84(4):177-181 | DOI: 10.31482/mmsl.2015.022

EBOLA OUTBREAK IN WEST AFRICAReview article

Vanda Boštíková ORCID...1*, Miloslav Salavec2, Radek Sleha ORCID...1, Petr Prášil3, Jan Marek ORCID...1,4, Ondřej Soukup ORCID...1,4, Kamil Kuča ORCID...1,4
1 Faculty of Military Health Sciences, University of, Hradec Kralove, Czech Republic
2 Department of Dermatovenerology, Charles University Medical School and University Hospital, Hradec Kralove, Czech Republic
3 Department of Infectious Diseases, Charles University, Medical School and Univeristy Hospital, Hradec Kralove, Czech Republic
4 Biomedical Research Center, University Hospital of Hradec Kralove, Hradec Kralove, Czech Republic

Viral hemorrhagic fevers (VHFs) represent a collection of illnesses caused by several distinct viral families. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause life-threatening diseases. In general, the term "viral hemorrhagic fever" describes a severe multisystem syndrome. Typical for this syndrome is a systemic damage of vascular system often accompanied by hemorrhages.Ebola is a type of VHF, along with Marburg, Lassa, dengue, Rift Valley, and yellow fever. VHFs are RNA viruses whose survival is dependent on animal or insect hosts. Ebola hemorrhagic fever initially makes the leap from an animal reservoir to a human, and can then be passed from human to human through direct contact.In the autumn and winter of 2014 every day professional and popular press published new information about Ebola outbreak in West Africa. It was not just data related to the number of patients, new recommendations and protocols, information about testing of potential vaccines, but also theoretical works that tried to analyze the situation and data.

Keywords: textviral hemorrhagic fevers; Lassa virus; Junin virus; Machupo virus; Omsk hemorrhagic fever; Kyasanur forest fever; yellow fever, dengue; Ebola; Marburg; Rift Valley fever virus; hantaviruses

Received: November 21, 2015; Revised: November 30, 2015; Published: December 4, 2015  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Boštíková, V., Salavec, M., Sleha, R., Prášil, P., Marek, J., Soukup, O., & Kuča, K. (2015). EBOLA OUTBREAK IN WEST AFRICA. MMSL84(4), 177-181. doi: 10.31482/mmsl.2015.022
Download citation

References

  1. www.cdc.gov
  2. Suzuki, Y., Gojobori, T. The origin and evolution of Ebola and Marburg viruses. Mol Biol Evol. 1997,14, 800 - 806. Go to original source... Go to PubMed...
  3. Center for disease control and prevention. Chronology of Ebola hemorrhagic fever outbreaks. Accessed: August 2014. Available from: http://www.cdc.gov/vhf/ebola/resources/outbreak-table.html.
  4. Pigott, D.M., Golding, N., Mylne, A. Mapping the zoonotic niche of Ebola virus disease in Africa. eLife 2014, 3:e04395. DOI: 10.7554/eLife.04395 Go to original source... Go to PubMed...
  5. Sanchez, A., Ksiazek, T.G., Rollin, P.E. Reemergence of Ebola virus in Africa. Emerg Infect Dis. 1995, 1, 96-97. Go to original source... Go to PubMed...