MMSL, 2012 (vol. 81), issue 3
MEDICAL SUPPORT IN ASYMMETRIC OPERATIONSOriginal article
Milan Růžička, Vojtěch Humlíček, Petr Witt
MMSL 2012, 81(3):90-95 | DOI: 10.31482/mmsl.2012.014 
In recent years, experience from the conduct of operations has shown changes in their contemporary leadership. Increasingly, asymmetric operations step to the fore. The medical support of these operations is one of conditions for their success. Results of exploratory research methods indicate the need for adjustments with regards to education, training as well as organization of medical support of the tactical units within asymmetric operations.
IN VITRO SKIN PERMEATION OF DETERGENTS AND DETERGENT-BASED DECONTAMINATION MIXTUREOriginal article
Jan Misík, Růžena Pavlíková, Jiří Cabal, Denis Josse, Kamil Kuča
MMSL 2012, 81(3):96-99 | DOI: 10.31482/mmsl.2012.015
The purpose of this study was to assess the ability of selected detergents (althosan MB 50%, triton X) and one commercial decontamination mean (Argos™) to permeate the pig skin, which could indicate a potential toxic side effect of mass casualty decontaminants. A method of static diffusion cells and UV spectrometry was used to evaluate the skin permeation. All tested agents did not permeate the skin in detectable amounts as 5% water solutions. In concentrated form, triton X and Argos™ did not permeate the skin whereas althosan MB 50% shown specific permeation rate of 6.134 μg.cm-1 in 24 hours.
BURKHART AND KARAS METHODS OF OPERATIVE TREATMENT OF MASSIVE ROTATOR CUFF TEARSOriginal article
Libor Urbánek
MMSL 2012, 81(3):100-112 | DOI: 10.31482/mmsl.2012.016
The most complex topic is represented by operative treatment of type IV lesions of rotator cuff. Palliative arthroscopic resection of rotator cuff did not produce optimal results. We thus intend to evaluate the newly implemented surgical techniques at our department.Fifty-six patients with type IV rotator cuff lesions were treated surgically between October 2007 and December 2010. In 6 patients, combined operations had to be performed because of their pathology, and these were not included in detailed evaluation. The population selected for detailed evaluation of new surgical techniques included 50 patients (mean age: 59 years, range: 41-73 years)....
POSSIBILITIES OF THE QCM METHOD EMPLOYMENT TO DETERMINATION OF TOXIC COMPOUND CONCENTRATION IN DEPENDENCE OF BARRIER MATERIALS RESISTANCEReview article
Pavel Otřísal, Stanislav Florus
MMSL 2012, 81(3):113-118 | DOI: 10.31482/mmsl.2012.017
This paper points to some aspects of possible usage of a QCM method within a set of toxic compounds permeated concentration based on a permeation curves rate and after underdone calibration of a measurement system. Presented assesses can be used not only in favour of the Czech Armed Forces Chemical Corps specialists but subsequently also in favour of personnel protection for those working in an area with toxic compounds appearance.
EFFECT OF ACETYL-L-CARNITINE PRETREATMENT ON RADIATION PNEUMONITIS AND L-ARGININE-NO METABOLIC PATHWAYOriginal article
Andrea Babicová, Jaroslav Pejchal, Zuzana Havlínová, Martina Řezáčová, Klára Kubelková, Jaroslav Chládek, Aleš Tichý, Jiřina Vávrová, Lenka Zárybnická, Eva Novotná, Kamil Kuča, Zuzana Šinkorová
MMSL 2012, 81(3):119-128 | DOI: 10.31482/mmsl.2012.018
Purpose: The purpose of our study is to examine the effect of acetyl-L-carnitine (ALC) pretreatment on radiation pneumonitis and L-arginine-nitric oxide (NO) metabolic pathway after local chest irradiation.Materials and methods: Female Wistar rats were pretreated with either phosphate buffer saline or ALC and locally irradiated by a dose of 15 Gy onto the chest. Samples were collected 7 weeks after irradiation. Exhaled NO was monitored using chemiluminiscence method. In plasma and bronchoalveolar lavage (BAL) fluid, nitrite/nitrate (NOx) and malondialdehyde were measured by high-performance liquid chromatography.Total protein concentration...
USING THE PIG'S BRAIN ACETYLCHOLINESTERASE IMMOBILIZED ON A TEXTILE FIBER TO TEST THE ANTIDOTES OF NERVE AGENT POISONINGS - PART IOriginal article
Ivana Moravcová, Jiří Cabal, Jitka Šandová
MMSL 2012, 81(3):129-137 | DOI: 10.31482/mmsl.2012.019
An integral part of the research and development of new antidotes against nerve agents (herein referred to as NAs) is the verification of their efficacy by means of in vitro tests. The purpose of these tests is to verify the ability of an antidote to protect cholinesterases from inhibition or to reactivate inhibited cholinesterases. For this purpose cholinesterases of different species and with a different degree of purification are traditionally used. Using immobilized cholinesterases proves to be new and advantageous for a number of reasons. The authors of the presented work verified the usability of Detehit detector (Oritest Praha Ltd) containing...
CENTER FOR TRANSFER OF BIOMEDICAL TECHNOLOGIES HRADEC KRALOVE HAS BEEN LAUNCHEDLetter to the editor
Lucie Bartošová
MMSL 2012, 81(3):138-139
On the 1st July 2012 the Center for Transfer of Biomedical Technologies (CTBT) started its operation at the premisses of University Hospital Hradec Kralove. The center provides intellectual property protection assistance and other commercialization support to researchers of University Hospital Hradec Kralove and partner organizations - Faculty of Military Health Sciences of University of Defence, Faculty of Informatics and Management and Faculty of Science of University Hradec Kralove. CTBT links industrial partners interested in commercializing ...
DEVELOPMENT OF AN INTRAVENOUS FORMULATION OF HI-6: A WORKSHOPLetter to the editor
John Mikler
MMSL 2012, 81(3):140 | DOI: 10.31482/mmsl.2012.021
Organophosphorous compounds are the basis of many insecticides and nerve agents. In military and first responder situations, organophosphorous (OP) poisoning is treated immediately with nerve agent antidote autoinjectors. The specific antidotes contained within these autoinjectors vary by country. In certain situations, such as severe exposure, skin exposure to low-volatility nerve agents and protracted low-dose exposure, there is a requirement for in-hospital care of OP nerve agent poisoned casualties. This treatment is more effectively carried out using...